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brain-injury Clinical Trials

A listing of brain-injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 375 clinical trials
K Kristi E Pruiksma, PhD

Behavioral Insomnia Treatment in Mild Traumatic Brain Injury

This is a single site, two-armed random controlled trials (RCT) comparing six sessions of Cognitive Behavioral Therapy for Insomnia (CBT-I) with four sessions of Brief Behavioral Therapy for Insomnia (BBT-I) in service members with comorbid insomnia and prolonged postconcussive symptoms present for at least 3 months after Mild Traumatic Brain …

18 - 45 years of age All Phase N/A
P Paul R King, PhD

Problem-Solving Training for Concussion

Mild traumatic brain injury (mTBI), also known as concussion, is a common injury sustained by Veterans. While most individuals who sustain mTBI experience a complete recovery within several weeks of injury, many Veterans with history of mTBI report frequent and long-lasting neurobehavioral complaints and functional impairment. Though research suggests that …

18 years of age All Phase N/A

Exercise Reset for Concussion in a Military Environment

Our primary objective is to show that early, personalized aerobic exercise treatment safely improves concussion recovery, speeds RTD, and reduces persistent symptoms in CSM. Our secondary objectives include demonstrating the clinical utility of our March-in-place test and determining fundamental mechanisms for the effect of exercise rehabilitation on concussion recovery.

18 - 40 years of age All Phase N/A
O Omar Soliman

Tranexamic Acid in Traumatic Brain Injury

In this study, our aim is to investigate the role of tranexamic acid for modulating the inflammation in patients with traumatic brain injury (TBI).

18 - 65 years of age All Phase 3
I Ishita Basu

Early Neuromodulation in Traumatic Brain Injury

The two goals of the proposed study are: (1) To determine how brain activity changes with cognitive recovery over time from acute to chronic phases of traumatic brain injury (TBI). (2) To determine how the time of anodal transcranial electrical stimulation (A-tES) administration affects cognitive performance and brain activity in …

18 - 80 years of age All Phase N/A
C Christina Rostrup Kruuse, PhD

Robot-assisted Training After Traumatic Brain Injury and Disorders of Consciousness

The goal of this randomised cross-over feasibility trial is to investigate two intensive robot-assisted training therapies in the early rehabilitation phase after traumatic brain injury and disorders of consciousness. The main questions it aims to answer are: Is the protocol feasible concerning inclusion in the study? Is the protocol feasible …

18 years of age All Phase N/A
E Emma Kaplan

TeleRehab to Restore Upper Limb Function in People With Chronic TBI

The study aims to inform the subsequent large-scale clinical trial focused on using telerehabilitation techniques and technologies to improve upper limb function and quality of life.

45 - 75 years of age All Phase N/A
C Cecilia Valdovinos, NP

Treatment of Acute PTH With a CGRP Receptor mAb in Military Service Members and Civilians With mTBI

This study aims to assess the effect and safety of erenumab compared to placebo for the treatment of acute posttraumatic headache (PTH) in military service members and civilians with mild traumatic brain injury (mTBI).

18 - 50 years of age All Phase 2
S Sara P Chrisman, MD MPH

Concussion Recovery and Support Program

Pilot randomized controlled trial (RCT) comparing a novel intervention Concussion Recovery and Support Program (CRISP) for adolescents and young adults (AYA) 18-29 yo with concussion/ mild TBI.

18 - 29 years of age All Phase N/A
A Alessia Vargiolu, PhD

Mesenchymal Stromal Cells for Traumatic Brain Injury

Traumatic Brain Injury (TBI) is an alteration of brain function caused by an external force. Long-term mortality in TBI is substantial, TBI survivors can develop chronic progressive disabilities and have a life expectancy shortened by 6 years. Treatment consists in supportive therapy directed at prevention of second insults, but no …

18 - 70 years of age All Phase 2

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