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brain-injury Clinical Trials

A listing of brain-injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 364 clinical trials
S Stéphane KREMER, MD

Pilot Study Evaluating brainQuant's Ability to Detect Alterations in White Matter in Diffusion MRI, Indicative of Post-traumatic Lesions

Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease described in boxing, but also in contact sports such as American football. Soccer, due to repeated headers, could also be associated, albeit to a lesser degree, with the development of this type of pathology. Indeed, it has been shown that playing soccer …

32 - 60 years of age Male Phase N/A
I Ishita Basu

Early Neuromodulation in Traumatic Brain Injury

The two goals of the proposed study are: (1) To determine how brain activity changes with cognitive recovery over time from acute to chronic phases of traumatic brain injury (TBI). (2) To determine how the time of anodal transcranial electrical stimulation (A-tES) administration affects cognitive performance and brain activity in …

18 - 80 years of age All Phase N/A
O Omar Soliman

Tranexamic Acid in Traumatic Brain Injury

In this study, our aim is to investigate the role of tranexamic acid for modulating the inflammation in patients with traumatic brain injury (TBI).

18 - 65 years of age All Phase 3
M Miranda M Lim, MD, PhD

Pilot Study of BCAA on Sleep

Individuals will be recruited from the VA Portland Health Care System and the community affiliated with Oregon Health & Science University. Traumatic brain injury status will be assessed as a contributing factor. Subjects will be randomized to one of 3 groups (BCAA or one of 2 placebo conditions) and instructed …

18 - 89 years of age All Phase N/A
C Christina Rostrup Kruuse, PhD

Robot-assisted Training After Traumatic Brain Injury and Disorders of Consciousness

The goal of this randomised cross-over feasibility trial is to investigate two intensive robot-assisted training therapies in the early rehabilitation phase after traumatic brain injury and disorders of consciousness. The main questions it aims to answer are: Is the protocol feasible concerning inclusion in the study? Is the protocol feasible …

18 years of age All Phase N/A
K Karen Sagher

Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures

This research is studying a device already approved by the Food and Drug Administration (FDA) to treat wound closures. Researchers are studying a large group of people to continue to learn information about the safety of the STRATAFIX suture and how people's bodies react to using it over a long …

18 years of age All Phase 4
E Emma Kaplan

TeleRehab to Restore Upper Limb Function in People With Chronic TBI

The study aims to inform the subsequent large-scale clinical trial focused on using telerehabilitation techniques and technologies to improve upper limb function and quality of life.

45 - 75 years of age All Phase N/A
J Jennifer Robles, RN

Treatment of Acute PTH With a CGRP Receptor mAb in Military Service Members and Civilians With mTBI

This study aims to assess the effect and safety of erenumab compared to placebo for the treatment of acute posttraumatic headache (PTH) in military service members and civilians with mild traumatic brain injury (mTBI).

18 - 50 years of age All Phase 2
S Sara P Chrisman, MD MPH

Concussion Recovery and Support Program

Pilot randomized controlled trial (RCT) comparing a novel intervention Concussion Recovery and Support Program (CRISP) for adolescents and young adults (AYA) 18-29 yo with concussion/ mild TBI.

18 - 29 years of age All Phase N/A
R Robert Rinaldi, MD FAAPMR

Brain Injury Education and Outpatient Navigation-1stBIEN

Traumatic brain injury (TBI) is a significant problem for U.S. Hispanic children. Compared to non-Hispanic children, Hispanic children have higher long-term disability and lower health related quality of life, even though differences are not present at hospital discharge. Rehabilitation decreases disability, but needs timely initiation, and long treatments in hospitals, …

6 years of age All Phase N/A

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