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brain-injury Clinical Trials

A listing of brain-injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 375 clinical trials
R Rocio Norman, PhD

Auditory Plasticity Training

The investigators are working on a project to help people who have had mild brain injuries hear better. Sometimes, these injuries can make it hard for people to hear clearly, especially in noisy places or when trying to tell where sounds are coming from. The project is testing special training …

18 - 55 years of age All Phase N/A
L Laura Kurdziel

Regulation of Emotion, Sleep Extension, and mTBI

Concussions are incredibly common, and often result in severe and long lasting symptoms, including, but not limited to, sleep deprivation and emotion dysregulation. This study aims to demonstrate the therapeutic benefits of sleep extension (napping) on emotion regulation in individuals after they sustain a concussion. Thus, sleep extension may be …

18 - 35 years of age All Phase 1
P Peng-fei Yang, MD

Acute EpiDural Hematoma Treated With Middle Meningeal Artery Embolization: a Randomized Trial (AEDH-MT)

A prospective, multicenter, randomized controlled, open-label, blinded endpoint evaluation study.

18 years of age All Phase N/A

Studying Anakinra to Reduce Secondary Brain Damage After Spontaneous Haemorrhagic Stroke

Spontaneous intracerebral haemorrhage (sICH) is the deadliest stroke subtype yearly affecting over 6000 patients in the Netherlands. Treatment options are very limited. Inflammation plays a vital role in the development of sICH-related secondary brain injury (SBI). Within 4 hours after sICH onset, blood components and thrombin induce the release of …

18 years of age All Phase 2
S Sedsel Pedersen, PhD studuent

Get Going After concussIonN Lite

Background Concussion affects around 25 000 people each year in Denmark. A large research initiative (GAIN 2.0) has been established, and the current study is a part of this initiative. Aims To develop and test the efficacy of a novel intervention for people with persistent post-concussional mild-to-moderate symptoms: "Get going …

18 - 60 years of age All Phase N/A
W William Panenka

REhabilitation of MEMory Symptoms After BRain Concussion

Persistent memory symptoms after concussion are common, and likely perpetuated by unhelpful illness beliefs and coping behaviors. Results from a pilot study suggested that traditional cognitive rehabilitation and a novel cognitive-behavioral therapy (CBT) protocol were both associated with improvements in subjective memory functioning. The present study will more definitively compare …

18 - 59 years of age All Phase N/A
D Daniel J Corwin, MD, MSCE

Facilitating Access to Specialty Treatment

The goal of this hybrid implementation-effectiveness study is to evaluate the effectiveness (hastened recovery times) and feasibility (fidelity in connecting to concussion specialty care) of a novel mobile health intervention, designed to reduce disparities in access to specialty care through the use of remote patient monitoring (RPM) to facilitate care …

13 - 18 years of age All Phase N/A
M Michael H Marcussen, Ph.D.

The Effect of Creatine Monohydrate on Persistent Post-concussive Symptoms

The purpose of this study, is to investigate whether creatine monohydrate as a supplement reduces the number and severity of symptoms in patients with persistent post-concussive symptoms through self-reported post-concussion symptoms questionnaires.

20 - 45 years of age All Phase N/A
T Tiana Maple

Eye Recovery Automation for Post Injury Dysfunction (iRAPID)

This study will test a portable virtual reality (VR) system with integrated eye tracking called Virtual Eye Rotation Vision Exercises (VERVE). The proposed VERVE platform will deliver vergence therapy in an automated manner. This research will involve 30 non-traumatic brain injury (TBI) binocularly normal (BNC) Veterans and 50 post-traumatic convergence …

18 - 40 years of age All Phase N/A
T Timothy Morris, PhD

Walking After Traumatic Brain Injury in Older Adults

The goal of this study is to test the effect of a planning, reminders, and micro-incentives intervention verses regular health education facts on physical activity participation over 12-weeks, in older adults who have previously suffered a non-penetrating mild or moderate TBI. Participants will provide information and be screened for eligibility …

65 - 80 years of age All Phase N/A

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