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Stress Clinical Trials

A listing of Stress medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 875 clinical trials
F Franziska Schmitt, M.Sc.

The Effects of Chicory Root-derived Prebiotic on Mood and Stress Responsiveness in Healthy Adults With Mild to Moderate Levels of Stress and Anxiety

Emerging evidence from preclinical research suggests that prebiotic fibres may play a beneficial role in supporting mental health through modulation of the gut-brain axis-a complex communication network linking the gastrointestinal tract and the central nervous system. Chicory root-derived prebiotic fibre, already well-established for its positive effects on glycaemic control and …

18 - 70 years of age All Phase N/A
E Emily L Belleau, PhD

Neural Correlates of Stress and Perceived Control in Adolescent Depression

Lack of perceived control, particularly during stress, has been critically implicated in major depressive disorder (MDD) and anhedonic symptoms, especially among female adolescents; yet the neural underpinnings of perceived control disruptions in MDD remain poorly understood. Using functional magnetic resonance imaging with a novel "value of control task" in conjunction …

14 - 18 years of age Female Phase N/A
S Suwasin Udomkarnjananun, M.D.

Furosemide Stress Test Predicting Early Graft Function in Kidney Transplantation

Furosemide is an old drug that has been used frequently in the postoperative period of kidney transplantation, aiming to achieve adequate urine output. There is no previous study that directly evaluate the urine response to standardized dose of furosemide in the postoperative period. The objective is to measure the urine …

18 - 80 years of age All Phase N/A
Q Qian Lu

Expressive Writing for the Management of Stress in Cancer Survivors

This clinical trial evaluates the effect of expressive writing for the management of stress in cancer survivors. Cancer diagnosis and treatment are associated with increased stress in cancer survivors related to concerns about family, career, relationships, finances, side effects of treatment, and death. This stress can be further exacerbated by …

18 years of age All Phase N/A

Ketamine in OCD: Efficacy and Effects on Stress and Cognition

The main goal of this trial is to demonstrate therapeutic efficacy of low dose ketamine in patients with OCD. We expect that ketamine will alleviate symptoms in the hours following application, but also - if effective - that the anti-OCD effects might last for several days after a single infusion.

18 years of age All Phase N/A

Effects of Stellate Ganglion Block in Post-traumatic Stress Disorder

This study will enroll patients meeting Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for post-traumatic stress disorder (PTSD). Following an initial screening visit, clinical assessment, and enrollment, subjects will be randomized into treatment and placebo arms. Both cohorts will undergo a pre-intervention functional magnetic resonance imaging …

18 - 65 years of age All Phase 4
K Keely A Muscatell, PhD

Beta-Blocker Influences on Inflammatory and Neural Responses to Stress

The purpose of this study is to map the neural and molecular mechanisms underlying psychological stress-induced changes in inflammation which could reveal new targets for intervention to reduce the risk of cardiovascular disease.

18 - 30 years of age All Phase 4
B Bela Mrinakova, MD

Stress-Reducing Intervention in Patients With Colorectal and Breast Cancer

The goal of this interventional study is to test the heart-rate variability biofeedback intervention (HRV BI) in 2 cohorts of patients. Cohort A will evaluate the effect of the addition of HRV BI in patients with breast cancer treated in the neoadjuvant setting (vs. standard of care alone, SOC) followed …

18 years of age All Phase N/A
B Barney Gadson

The LEADS Trial (Linking Exericise for Advancing Daily Stress Management)

Chronic stressors have wide-reaching harmful effects on the physical, social, and psychological well-being of many African American (AA) families. These stressors place some AA adolescents, who already experience low rates of physical activity (PA) and high rates of obesity, at even greater risk for developing chronic diseases. Previous family-based interventions …

11 - 16 years of age All Phase N/A
E Emily L Belleau, PhD

Stress Dynamics and Familial Risk for Depression in Female Adolescents

Stress and a parental history of major depressive disorder (MDD) are among the strongest risk factors for future development of MDD. Studies have shown that having a parental history of MDD may be associated with behavioral, psychophysiological, and hormonal responses to stress that are associated with poorer stress coping. . …

13 - 15 years of age Female Phase N/A

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