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Stress Clinical Trials

A listing of Stress medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 909 clinical trials
K Karen Saban, RN, PhD

The Impact of a Race-Based Stress Reduction Intervention

The goal of this clinical trial is to learn whether a stress reduction program called Resilience, Stress, and Ethnicity (RiSE) improves well-being, inflammation, and the epigenome in African American (AA) women who have risk factors for heart or metabolic disease. The main question it aims to answer is whether an …

50 - 75 years of age Female Phase N/A
W Wen Li, PhD

A Neurosensory Account of Anxiety and Stress (Study 2)

This study will take a basic neuroscience approach to investigate pathological mechanisms underlying PTSD. Additionally, the study aims to identify how Transcranial Alternating Current Stimulation (tACS) brain stimulation can modulate and correct neural networks and related emotions of anxious arousal and hypervigilance, with the goal of assessing tACS brain stimulation …

18 - 50 years of age All Phase N/A
J Jacob White

Neuromodulation of Brain and Emotional Responses to Psychological Stress

Investigators are conducting this study to test if temporarily and non-invasively stimulating the brain will affect the emotional response to stress in healthy participants. Participants will perform a series of tasks while completing an MRI scan. After this, participants will be randomized to undergo transcranial magnetic stimulation (TMS) at two …

30 - 50 years of age All Phase N/A
M Molly Maxfield, PhD

Increasing Physical Activity Through Social Support and Stress Resilience

The goal of this clinical trial is to learn the effects of technology enhancements when combined with basic education, goal-setting, and self-monitoring to increase physical activity among older adults living alone, experiencing subjective cognitive decline, and currently engaging minimal physical activity (60 minutes or less of moderate to vigorous physical …

60 years of age All Phase N/A
A Alexs Matias, MS

Vascular Function and Oxidative Stress in Emergency Medical Responders

The goal of this clinical trial is to characterize blood vessel function and oxidative stress (a harmful condition that damages cells and tissues) in emergency medical technicians (EMTs). The main questions it aims to answer are: Does an overnight shift work in emergency medical technicians reduce blood vessel function and …

20 - 40 years of age All Phase N/A
R Richard Kanaan, CTT, MBBCH, PhD

Silexan in the Treatment of Posttraumatic Stress Disorder Trial

Posttraumatic stress disorder (PTSD) is a common and debilitating mental illness. Current treatments for PTSD include psychotherapy and antidepressant medications. Many patients are unable to tolerate psychotherapy for PTSD and drop out of it. In addition, its effectiveness is limited. Up to 50 percent of patients who receive psychotherapy do …

18 years of age All Phase 3
F Fernanda Mesa-Chavez, MD, MSc

Online Mindfulness-based Stress Reduction for Patients Receiving Chemotherapy

The goal of this prospective, waitlist-controlled, 1:1 randomized study is to evaluate if an online mindfulness-based stress reduction (MBSR) intervention reduces treatment-related stress levels among patients with breast cancer receiving chemotherapy. The main questions it aims to answer are: Does an online MBSR intervention reduce stress levels (measured through the …

18 years of age Female Phase N/A

Effect of Attentional Therapy on Post-traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) is associated with an attentional bias towards negative stimuli, which is supposed to contribute to the development and the maintenance of the disorder. We recently showed using eye-tracking evidenced two types of AB towards negative stimuli: a "physiological AB" found both in healthy and individual with …

18 - 60 years of age All Phase N/A
F Franziska Schmitt, M.Sc.

The Effects of Chicory Root-derived Prebiotic on Mood and Stress Responsiveness in Healthy Adults With Mild to Moderate Levels of Stress and Anxiety

Emerging evidence from preclinical research suggests that prebiotic fibres may play a beneficial role in supporting mental health through modulation of the gut-brain axis-a complex communication network linking the gastrointestinal tract and the central nervous system. Chicory root-derived prebiotic fibre, already well-established for its positive effects on glycaemic control and …

18 - 70 years of age All Phase N/A

Effects of Stellate Ganglion Block in Post-traumatic Stress Disorder

This study will enroll patients meeting Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for post-traumatic stress disorder (PTSD). Following an initial screening visit, clinical assessment, and enrollment, subjects will be randomized into treatment and placebo arms. Both cohorts will undergo a pre-intervention functional magnetic resonance imaging …

18 - 65 years of age All Phase 4

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