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high-blood-pressure Clinical Trials

A listing of high-blood-pressure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 904 clinical trials
f freemanstudies

MegaNatural BP® GSE on Blood Pressure and Cardiometabolic Risk Factors

Inflammation and stressors can interfere with the function of the lining of blood vessels and insulin activity, therefore, investigators are aiming to see how the Grape seed Extract (GSE) called MegaNatural BP can help with limiting the effects of these factors. This research will study the effects of taking 150mg …

40 - 60 years of age All Phase N/A
B BeomSeok Kim, M.D, Ph.D

Efficacy and Safety of Telmisartan Compared With Losartan

A study to evaluate the efficacy and safety of telmisartan compared with losartan in patients with diabetic nephropathy and hypertension

19 - 75 years of age All Phase 4

Validation Study of CART BP as a Wearable Cuffless Blood Pressure Monitor

This study aims to evaluate the accuracy of the CART BP, a medically approved ring-type blood pressure monitor, in comparison to the traditional auscultatory method using a dual-head stethoscope. The comparison is conducted in accordance with the 2023 European Society of Hypertension (ESH) Recommendations, focusing on patients with suspected hypertension …

18 - 80 years of age All Phase N/A
Y Yun Ni Lee

Diagnosing Variable Primary Aldosteronism.

The goal of this observational study is to see if there is a cyclical or exaggerated diurnal variation in aldosterone production in people with Primary Aldosteronism.

18 years of age All Phase N/A

Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study

This research study aims to learn more about the impact the hormone aldosterone on the heart. Primary aldosteronism is a condition where the body's adrenal glands make too much of the hormone aldosterone, which can cause high blood pressure and increase the risk of heart and kidney disease. Treatment with …

18 - 85 years of age All Phase 4
Y Yu He, MD

Retinal Vascular Manifestations in Patients With Common Internal Diseases on OCTA Tomography Angiography

Hypertension, diabetes mellitus, and dyslipidemia are common internal diseases, and all diseases are atherosclerosis risk factors. Previous studies applied color fundus photography to analyze retinal vascular changes (including exudation, hemorrhage, neovascularization, etc.) in patients with hypertension or diabetes, but the examination results could not be quantified. This study intends to …

18 years of age All Phase N/A
G Grégoire Wuerzner, MD

Performance of the Aktiia Optical Blood Pressure Monitoring Device Against Double Auscultation

This study with N = 225 participants (1 cohort of a minimum of 85 and maximum of 140 participants, and an additional cohort with 85 participants) over 9 visits has been designed to assess the accuracy of Aktiia.product-us systolic and diastolic blood pressure measurements against double-auscultation reference measurements. In order …

21 - 85 years of age All Phase N/A
Z Zhiming Zhu, MD

Efficacy of Spironolactone Combined With Antihypertensive Drugs in Patients With Primary Aldosteronism

The goal of this observational study is to learn about the optimal dose of spironolactone treatment and the long-term outcomes on cardiovascular and cerebrovascular events in patients with lateralized PA who are unwilling to undergo surgery. The main question it aims to answer is: What is the long-term effect of …

30 - 65 years of age All Phase N/A
N Nehal Vekariya, MS

Polygenic Risk Score Implementation and Stratification for Managing Blood Pressure

In a multi-ethnic population, a genome-wide polygenic risk score (PRS) for systolic blood pressure (SBP), incorporating over one million common genetic variants, predicts blood pressure (BP) traits and the risk of adverse cardiovascular events beyond traditional risk factors. Delivering SBP PRS information to young and middle-aged adults with hypertension (HTN) …

18 - 55 years of age All Phase N/A
A Austin T Robinson, PhD

Ketone Ester And Salt (KEAS) in Older Adults

Most Americans consume excess dietary salt based on the recommendations set by the American Heart Association and Dietary Guidelines for Americans. High dietary salt impairs blood pressure control by affecting systemic blood vessels and the kidneys. These changes contribute to excess salt consumption being associated with increased risk for chronic …

60 - 85 years of age All Phase N/A

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