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high-blood-pressure Clinical Trials

A listing of high-blood-pressure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 865 clinical trials
I Isabel Blanco, MD, PhD

Urban-training Intervention in Pulmonary Hypertension (UTHAP)

Pulmonary rehabilitation is effective in the treatment of pulmonary hypertension (PH). However, the beneficial effects of such intervention have been seen to disappear over time in other chronic diseases. The objective of the project is to evaluate the efficacy of an urban exercise program after a rehabilitation program and to …

18 - 99 years of age All Phase N/A
J Jian Cui

The Venous Distension Reflex and Orthostatic Hypertension

This research is being done to find out whether distension of veins in legs will cause a rise in blood pressure (orthostatic hypertension).

18 years of age All Phase N/A
M Maria A. Pabon, MD

Spironolactone to Improve Pregnancy-Associated Hypertension Trajectories

The hypertensive disorders of pregnancy (preeclampsia and gestational hypertension) are associated with increased long-term maternal risk of developing cardiovascular disease. Recent evidence suggests that activation of the mineralocorticoid receptor promotes ongoing susceptibility to hypertension in women following hypertensive disorders of pregnancy. In addition, women with overweight/obesity are at increased risk …

18 years of age Female Phase 2
L Laleh Zarrinkoob, MD, PhD

Hypertension and Cerebrovascular Hemodynamics in General Anaesthesia

During anesthesia, blood pressure-raising medications are often required to achieve an adequate blood pressure level. However, there is limited knowledge about what constitutes an adequate blood pressure to ensure sufficient blood flow to the brain. This project aims to map the relationship between blood pressure and brain blood flow using …

50 - 80 years of age All Phase N/A
A Amelie ya

Stenting Versus Neurosurgical Treatment of Idiopathic Intracranial Hypertension.

Idiopathic intracranial hypertension (HTICi) is a pathology, affecting young adults with a predominance of women, due to an increase in intracranial pressure, which may be associated with stenosis of the cerebral venous sinuses and whose origin remains unknown. This hypertension can lead to papillary edema (OP) which can lead to …

18 years of age All Phase N/A

Inhaled Treprostinil in Sarcoidosis Patients With Pulmonary Hypertension

This study aims to evaluate the efficacy and safety of inhaled treprostinil in subjects with sarcoidosis-associated interstitial lung disease and pulmonary hypertension.

18 - 99 years of age All Phase 2
L Lecarpentier Edouard, MD

Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy

A randomized clinical trial to assess the efficiency of acetylsalicylic acid (aspirin) 150 mg/day started before 20 weeks of gestation in the prevention on maternal and fœtal complications in pregnant women with chronic hypertension.

18 years of age Female Phase 3
E Emily C Smith, RN MPH

Treatment of Supine Hypertension in Autonomic Failure (CPAP)

Supine hypertension is a common problem that affects at least 50% of patients with primary autonomic failure. Supine hypertension can be severe and complicates the treatment of orthostatic hypotension. The purpose of this study is to assess whether continuous positive airway pressure (CPAP) decreases blood pressure in autonomic failure patients …

18 - 85 years of age All Phase N/A
V Victoria Jauk

Chronic Hypertension and Pregnancy 2 (CHAP2) Pilot Project

The CHAP2 study is designed to provide preliminary data for a larger multicenter study to assess whether treatment of stage 1 hypertension (HTN) in pregnancy improves maternal and or neonatal outcomes. The primary objective of this pilot study is to determine if anti-HTN treatment to BP<130/80mmHg in pregnant patients with …

14 - 89 years of age Female Phase 1
Y Yuxi Li, MD

Fractional Flow Reserve to Determine Atherosclerosis Renovascular Hypertension Stenting

Although randomized trials have demonstrated there is no benefit of renal-artery stenting in addition to medical therapy for patients with atherosclerosis renal artery stenosis, many patients indeed gained benefit in daily practices after stenting, such as reduction in blood pressure and recovery in renal functions. One important gap is that …

18 years of age All Phase N/A

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