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Dementia Clinical Trials

A listing of Dementia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 804 clinical trials

Assessment of Informal Support Provided by Caregivers at Different Stages of Alzheimer's Disease

In France, approximately 1,200,000 people aged 65 and over suffer from Alzheimer's disease or related disorders, of which Alzheimer's disease (AD) accounts for 70% of cases. This prevalence could double by 2050. The cognitive decline and progression to functional dependence that accompany AD are associated with a decline in quality …

60 years of age All Phase N/A

Safety and Efficacy of L. Lactis CKDB001 in Subjects With Early Alzheimer's Disease

Randomized, Placebo-Controlled, Double-Blind, 24-Week Proof-of-Concept Study to Evaluate the Safety and Efficacy of L. Lactis CKDB001 in Subjects With Early Alzheimer's Disease

55 - 85 years of age All Phase N/A
S Shanna C Trenaman

Lemborexant for Insomnia in a Patient With Dementia: An N-of-1 Trial

Insomnia is a highly common, chronic disorder that is distressful for the patient but also for caregivers and can give rise to a heavy burden on the healthcare team. Sleeping aids like benzodiazepines and other sedatives (e.g., zolpidem, zopiclone) have been widely used to help treat insomnia. However, sleeping aids …

years of age All Phase 4

Web-based Cognitive Behavioral Treatment for Insomnia in Dementia Caregivers

Over the next 30 years, more than 10 million persons living with dementia in the United States will receive care at home from an unpaid and untrained family caregiver. At home care is preferred by caregivers and persons with dementia alike, but increases the caregiver's risk of insomnia and related …

18 years of age All Phase N/A
S Shanshan Wang

A Robot-assisted Tailored Activity Programme for People With Dementia and Their Caregivers

To assess the feasibility and preliminary efficacy of the tailored activity programme on improving the physical inactivity of the caregiving dyads.

18 years of age All Phase 1
M Maya Elias, PhD, RN

A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors

Up to 25% of intensive care unit (ICU) survivors experience cognitive impairment comparable in severity to mild Alzheimer's disease and related dementias after hospital discharge. Older ICU survivors (ages 60 and older) are at highest risk for delirium and subsequent cognitive impairment, which contribute to higher risk for cognitive decline …

60 years of age All Phase N/A

An Open Label Dose Escalation Study of VY1706 in Participants With Early Alzheimer's Disease

VY1706 first in human study in early Alzheimer's Disease is a multicenter dose escalation study

30 - 80 years of age All Phase 1

A Study of Retinal Imaging to Detect Abnormal Protein Deposits Associated With Alzheimer's Disease

The purpose of this study is to test the use of a screening tool to detect changes in the eye that are associated with Alzheimer's disease in adult participants with memory issues. For each participant, the study will last up to one month and requires one visit to the research …

55 years of age All Phase N/A

Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department

Delirium is highly prevalent and very bad for patients with dementia. Delirium is a dangerous medical condition that occurs in 6-38% of older Emergency Department patients and 70% of ICU patients. A person who develops delirium in the ED or hospital has a 12 times higher odds of being newly …

65 years of age All Phase N/A
C Chih-Hsiang Yang

Mindful Walking Neural Correlates of Executive Function in SC Older Adults at Risk of Dementias

Mindful walking is a promising and practical strategy because it combines two activities known to support healthy aging: walking and mindfulness. Unlike many structured exercise programs, mindful walking is low intensity, accessible, and easier to sustain in daily life. It may be especially useful for older adults at elevated risk …

60 years of age All Phase 2

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