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Dementia Clinical Trials

A listing of Dementia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 807 clinical trials
M Mahmoud CHARIF, MD

Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease

The goal of this Multicenter observational pilot study is to Compare the specifics of musical engagement (behaviors related to music in everyday life) in subjects aged over 60 with Alzheimer s disease, Parkinson s disease and control subjects. The main questions it aims to answer are: The description of different …

60 years of age All Phase N/A

Sleep Impairment in Subjects at Risk of Developing Alzheimer's Disease

Alzheimer's disease (AD) is characterised by a progressive loss of memory and cognitive function. In the early stages of AD, there is a progressive accumulation of molecules: β-amyloid peptides (Aβ) in the brain. There is a link between the accumulation of Aβ peptides and the deterioration of sleep, but current …

50 - 85 years of age All Phase N/A
K Kendra Marks, AuD

OTC Hearing Aid and MCI

The goal of this study is to better understand if, in patients with mild to moderate hearing loss who are also experiencing mild cognitive impairment (MCI) or Alzheimer's disease and related dementias (ADRD), Over-the-Counter (OTC) hearing aids: improve communication Whether the magnitude of benefit depends on the patient's level of …

60 - 90 years of age All Phase N/A
S Seung-Hyun Kang

A Study to Compare PK Characteristics and Safety Profiles Between AD-228B and AD-2284

Primary endpoint of this study is to evaluate the pharmacokinetic characteristics of AD-228B in healthy subjects.

19 years of age All Phase 1
R Rosie Dunn, PhD

Family Interventions iN Dementia Mental Health Environments

Study Goal: Understand carers' needs when someone with dementia is in a mental health ward and develop strategies to support carers as partners in care. Research Questions: What are mental health wards like in terms of staff, patients, and current carer support? What do carers experience and need during admission, …

years of age All Phase N/A
F Francesca Farina, PhD

Development of a Personalized, Psychosocial Intervention for Menopausal Individuals With Elevated Dementia Risk

By age 45, women's lifetime risk of dementia is estimated to be 1 in 5. Two-thirds of people currently living with a dementia diagnosis are women, and-women make up the majority of carers for people with dementia. Because women bear a larger burden of the dementia epidemic, they tend to …

40 - 58 years of age Female Phase N/A
J Joana Carvalho, PhD

Multicomponent Exercise Program on Physical Function, Cognition and Falls Risk Among Older Adults Living in Nursing Homes (MOVE4CARE)

Can a multicomponent exercise program significantly improve physical and cognitive function and reduce fall rates among nursing home residents? To address this question, the present study aims to compare the effectiveness of a multicomponent exercise program with a stretching and relaxation program in nursing home residents.

65 years of age All Phase N/A
M Megan Thomas Hebdon

Financial Counseling for Dementia Family Caregivers in Early and Middle Adulthood

The goal of this National Institutes of Health (NIH) Stage 1a study is to develop and pilot test a research- and community-informed financial counseling and advocacy (FCA) intervention for dementia family caregivers in early and middle adulthood. The main question it aims to answer is: Is a research- and community-informed …

25 - 55 years of age All Phase N/A
H Hector Cervantes, MS

A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses

The goal of this clinical trial is to test 6 months of aerobic exercise in older adults who are 65 years or older and have mild cognitive impairment (MCI) or probable/possible mild Alzheimer's Disease. The main questions it aims to answer are: test the effects of aerobic exercise on aerobic …

65 years of age All Phase N/A
B Barry Greenberg, PhD

Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone

To investigate the effect of trazodone on sleep, hippocampal-dependent memory and hippocampal excitability. The investigators hypothesize that trazodone will improve total sleep time and proportion of time in Slow Wave Sleep (SWS).

55 years of age All Phase 2

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