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Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,189 clinical trials
J Jakob Wittenstein

Intelligent Lung Support in the Intensive Care Unit

The aim of this observational study is to test the IntelliLung decision support system based on artificial intelligence. This system is intended to help to set the ventilator. The study includes patients with and without ARDS (acute respiratory distress syndrome) who are receiving invasive mechanical ventilation, as well as patients …

18 years of age All Phase N/A
R Roy Sprooten, MD

Lung Cancer Organoids and Patient Derived Tumor Xenografts

Extra tissue will be taken from patient during a procedure in standard of care. Also, through an existing line, 10ml of extra blood will be drawn. From this material the investigator will try to establish matched normal and primary human lung cancer organoids.

18 years of age All Phase N/A
N Nowsheen Azeemuddin

A Study in Non-Small Cell Lung Cancer

A study to create control arms using current and future information in patients with lung cancer that has spread who have already received chemotherapy.

18 years of age All Phase N/A
F Francesco Agustoni

Ambispective Registry of Patients Affected by Lung Cancer

Lung cancer is one of the most common cancers and the leading cause of cancer-related death. It is often diagnosed late, and there are different types of lung cancer. Today, many patients benefit from targeted therapies and immunotherapy, which have improved survival. This study will create an ambispective clinical registry …

18 years of age All Phase N/A
P Phil Lacher

TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients

Hematopoietic stem cell transplant (HSCT) is an effective but toxic therapy and pulmonary morbidity affects as many as 25% of children receiving transplant. Early pulmonary injury includes diffuse alveolar hemorrhage (DAH), thrombotic microangiopathy (TMA) interstitial pneumonitis (IPS) and infection, while later, bronchiolitis obliterans is a complication of chronic GVHD associated …

- 24 years of age All Phase N/A
K Karen Mulholland Angelus

Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions

This multi-arm, multi-site study investigates the safety, tolerability, and efficacy of stem cell therapy for the treatment of various acute and chronic conditions. Clinically observed initial findings and an extensive body of research indicate regenerative treatments are both safe and effective for the treatment of multiple conditions.

18 years of age All Phase 1/2
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Collection of Lung Fluid and Tissue Samples for Research

This study will collect fluid and tissue specimens from the lungs and nose of healthy people and people with a history of lung infections. The specimens will be examined for differences between the two groups that may be associated with susceptibility to certain infections. Healthy normal volunteers and people with …

5 - 100 years of age All Phase N/A
Y Yeon Wook Kim, MD, PhD

Prospective Cohort of Diagnostic Bronchoscopy for Peripheral Lung Lesions

The primary objective is To evaluate the usefulness and safety of advanced guided bronchoscopy for histological diagnosis of peripheral pulmonary lesions. The Secondary objective is to establish a strategy that can most effectively use endoscopes for early diagnosis of lung cancer in a real-world care environment by identifying patient/clinical/image/procedure-related characteristics …

19 years of age All Phase N/A

Educating Smokers About Lung Cancer Screening Using Tobacco Quitlines

This implementation study will examine the best ways to refer heavy smokers to information about lung cancer screening.

18 years of age All Phase N/A
J Jean-Luc FELLAHI, Professor MD

Advanced Goal-Directed Impedancemetry Strategy for Lung Resection Surgery

High-risk patients scheduled for lung resection surgery are increasing and theoretically eligible to perioperative individualized goal-directed fluid therapy (GDFT). However, thoracic surgery is challenging for intraoperative stroke volume (SV) and/or cardiac output monitoring because it requires lateral positioning, one-lung ventilation, and open-chest condition. Pulse contour analysis and esophageal Doppler have …

18 - 80 years of age All Phase N/A

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