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Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,207 clinical trials
Y Yiyu Deng

Electrical Impedance Tomography-Based Prognostic Model for ARDS

This multicenter, prospective, observational study aims to develop and validate an EIT-based prognostic model for ARDS. By focusing on the pathophysiological characteristics of ARDS and the causes of ventilator-induced lung injury, the investigators intend to establish a prognostic model that reveals lung injury and heterogeneity, enabling risk stratification and guiding …

18 - 80 years of age All Phase N/A
J Jens Spiesshoefer, MD

Diaphragmatic Function as a Biomarker

Dyspnea is among the most common symptoms in patients with respiratory diseases such as Asthma, chronic obstructive pulmonary disease (COPD), Fibrosis, and Pulmonary Hypertension. However, the pathophysiology and underlying mechanisms of dyspnea in patients with respiratory diseases are still poorly understood. Diaphragm dysfunction might be highly prevalent in patients with …

18 years of age All Phase N/A
M Mary Pasquinelli, DNP

LUNG-07: Advancing Precision-Based Lung Cancer Screening: Implementation, AI-Guided Risk Stratification, and Biomarker Integration (CREST AI)

This research study aims to investigate methods for enhancing lung cancer screening. The study will investigate whether an artificial intelligence (AI) tool, known as Sybil, can aid in predicting the risk of lung cancer. The investigators will also examine whether expanding the screening criteria (based on the guidelines of the …

50 - 80 years of age All Phase N/A
L Lynn Vicente

Pan-Canadian Lung Cancer Observational Study (PALEOS)

A multicenter, ambispective observational study focusing on patients diagnosed with lung cancer in Canada identified after January 1, 2000 inclusive. This data will be combined with that from deceased patients identified.

18 years of age All Phase N/A
L Likun Hou, MD

Integrative Analysis of Large-cell Lung Cancer

Integrative analysis of LCLC

18 - 75 years of age All Phase N/A
J Julie A. Ward, BSN

Detection of Genetic Markers of Lung Cancer

The purpose of this research study is to determine the genetic changes and immunologic changes that are involved in the development and progression of bronchogenic lung cancer.

18 years of age All Phase N/A

Molecular and Genetic Analysis of Lung Cancer

Investigators use a genome-wide approach within a case-control design to identify SNPs that show evidence of association with lung cancer risk and survival.

18 years of age All Phase N/A
J Jacques BOUTROS, MD

Integrating Artificial Intelligence Into Lung Cancer Screening.

Lung cancer (LC) screening using low-dose chest CT (LDCT) has already proven its efficacy. The mortality reduction associated with LC screening is around 20%, much higher than the reduction in mortality associated with screening for breast, colon or prostate cancers. Implementing lung cancer screening on a large scale faces two …

18 - 80 years of age All Phase N/A
K Kathryn L Taylor, PhD

Tobacco Education and Lung Health Study (TEAL)

Primary Objective To compare two smoking cessation interventions among individuals undergoing lung cancer screening. Primary outcomes are: 3-month self-reported abstinence from cigarettes and 6-month self-reported and bioverified abstinence from cigarettes. Secondary Objectives 1) To evaluate reach and engagement overall and by subgroup (e.g., race and ethnicity, underinsured, readiness to quit). …

50 - 80 years of age All Phase 3
N Nathaniel Evans III, MD

A Registry for People With Lung Cancer

Participants will complete questionnaires before surgery, between 2 to 4 weeks after surgery, and 6 months after surgery.

18 years of age All Phase N/A

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