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lung-disease Clinical Trials

A listing of lung-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,186 clinical trials
A ABEL HUANG

Non-small Cell Lung Cancer With Central Nervous System Metastasis

Cerebrospinal fluid was obtained from the cerebrospinal cavity of non-small cell lung cancer patients with central nervous system metastasis, blood was obtained from veins, and metastatic lung cancer tumor tissue was obtained from surgically resected brain tumors or meningeal tumors. Then comprehensively analyze the exosomes contained in the aforementioned samples, …

20 - 90 years of age All Phase N/A
A Ashley Delgado

Tempus Sculptor Study: Small Cell Lung Cancer (SCLC) Observational Study

The study is a non-interventional evaluation of participants with SCLC who will receive diagnostic and (where possible) post-progression tumor tissue profiling, alongside plasma ctDNA biomarker profiling in addition to their standard of care therapy and disease surveillance.

18 years of age All Phase N/A
A Ali Abdulhussein, MD

"Lung Barometric Measurements in Normal And in Respiratory Distressed Lungs"

Little is known about how lung mechanics are affected during the very early phase after starting mechanical ventilation. Since the conventional method of measuring esophageal pressure is complicated, hard to interpret and expensive, there are no studies on lung mechanics on intensive care patients directly after intubation, during the first …

18 years of age All Phase N/A
T Tonya Hibbert

Rapid Autopsy Protocol for Patients With Small Cell Lung Cancer

This is pilot study to establish a rapid autopsy program in Small Cell Lung Cancer (SCLC) at the Indiana University Simon Comprehensive Cancer Center and outline the components necessary for tumor tissue collection.

18 years of age All Phase N/A
M Maja Guberina, PD Dr. med. (MD), specialist

PET-guided Radiotherapy for Patients With Small Cell Lung Cancer.

There is a prospective risk-adapted evaluation of the optimal dose of radiotherapy for definitive radiotherapy of locally advanced small cell lung cancer within the corridor recommended as standard therapy according to the current interdisciplinary S3 guideline of the German Cancer Society/Cancer Aid/AWMF

18 years of age All Phase N/A
R Roberto Gasparri, MD, PhD

Volatolomic and Proteomic Profile for Early Diagnosis of Lung Cancer

The goal of this prospective, case-control study is to discover the specific "omics" biomarkers of early stage of lung cancer using the non-invasive samples (breath, urine and serum) in a total of 200 subjects (100 healthy controls and 100 lung cancer patient). The main questions it aims to answer are: …

50 - 80 years of age All Phase N/A
T Thomas Mistretta, MS

Patient-Generated Health Data Collection During Chemoradiotherapy for Lung Cancer

This is an observational study involving the collection of patient-generated health data using an Apple Watch, a home pulse oximeter, and a smartphone during a course of proton beam radiotherapy for lung cancer. The study period over which this information is collected will range from the day of study enrollment …

18 years of age All Phase N/A
F Fengmei Guo, Ph.D

Personalized Ventilation Based on Ventilation-perfusion Mismatch and Lung Recruitability

This observational study will explore the effects of PEEP and position on regional lung ventilation-perfusion mismatch by electrical impedance tomography (EIT) in moderate-to-severe ARDS patients with different lung recruitability.

18 - 85 years of age All Phase N/A
W William Poncin

Lung Ultrasound for Physiotherapy in Hospitalized Patients With Respiratory Complications

This study aims to evaluate the relevance of using point-of-care lung ultrasound (LUS) in modifying the physiotherapist's treatment plan for patients hospitalized in a general ward.

18 years of age All Phase N/A
Y Yun Long

PEEP Titration and Lung Recruitment Potential Assessed by 3D EIT

In a population of ARDS patients, we explore the influence of different PEEP levels on regional ventilation distribution, ventilation homogeneity, and the center of ventilation, optimal PEEP and lung recruitment potential as well as the extent of lung collapse and overdistension as detected by 3D-EIT.

18 years of age All Phase N/A

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