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lung-disease Clinical Trials

A listing of lung-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,186 clinical trials
I Ivan Tancevski, MD

Prospective Registry of Eosinophilia With Respiratory Manifestations With Translational Research Identifying and Characterizing Eosinophils

Introduction: The etiology and therapy of eosinophilic lung diseases are still poorly understood. For individual forms of disease, such as eosinophilic asthma or eosinophilic granulomatosis with polyangiitis (EGPA), new therapeutic approaches exist that block the interleukin IL-5 or the IL-5 receptor. Eosinophilic manifestations of the respiratory tract can exclusively affect …

18 years of age All Phase N/A
W Wei Dai

Shared Decision Making in Patients With Lung Cancer

The objective of this study is to develop a Decision Aid for Lung Cancer Molecular Testing (DA_LCMT) and to facilitate shared-decision making in patients who were diagnosed with lung adenocarcinoma by intraoperative frozen pathology about whether to conduct the molecular testing.

18 years of age All Phase N/A
O Oksana Kamenskaya, PhD, MD

Radiotherapy Exposed Lung Injury: Effect on Functioning - Cohort

Prospective cohort research to study the state of oxygen metabolism, reserve capabilities of cardiovascular and respiratory systems in patients with breast cancer to create a program of prevention and rehabilitation of lung damage in the process of complex treatment of the disease. The aim of the study is to study …

18 years of age Female Phase N/A
M Marissa Rienton-Lim, CCRC

Collection of Sputum and Labeling for Lung Cancer

The primary objective of this study is to compare Assay results to diagnoses determined by currently accepted standards for lung cancer detection. This will be accomplished by analysis of sputum samples from three cohorts including healthy Participants, high risk Participants, and cancer patient Participants using the Assay as developed in …

21 years of age All Phase N/A
A Adrienne Scott

Evaluation Of The Lung Microbiome In NTM Bronchiectasis

A biomarker cohort study design is proposed to study whether specific airway microbiota alterations are associated with pulmonary Non-tuberculous mycobacteria (NTM) disease. In a cohort of 200 subjects suspected of having pulmonary NTM disease, the investigators will evaluate the airway microbiome using an aliquot of the induced sputum and upper …

18 years of age All Phase N/A
T Thomas Radtke, PhD

Nitric Oxide Lung Diffusing Capacity in Systemic Sclerosis

To date, two devices to measure nitric oxide lung diffusing capacity (DLNO) are commercially available in Europe. Previous research has shown systematic between-device differences in lung diffusing capacity outcomes in healthy people (Radtke et al. ERJ Open Res. 2021 Sep 13;7(3)). The extent and magnitude of between-device differences in people …

18 years of age All Phase N/A
J Jon Silversides

CMR Right Ventricular Contractile Reserve Following Lung Resection

Feasibility study investigating CMR dobutamine stress testing before and after lung resection

18 years of age All Phase N/A
M Mei-Chun Wan

Bronchial Response to Exercise After Double Lung Transplantation

This study aims to investigate the airway response to exercise and its association with breathlessness in double lung transplant recipients by comparing responses during 5-minute and 15-minute exercise durations.

20 years of age All Phase N/A
P Phuong Vu Hoang, PhD

Weaning Ventilator Using Heart, Lung And Diaphragm Ultrasound

Postextubation distress is detrimental to the prognosis of critically ill patients with successful spontaneous breathing trial. Failure to wean is known to be connected with heart, lung, and diaphragm problems. The aim of this study was to investigate how a composite model comprising diaphragm, lung, and heart ultrasonography indications could …

18 years of age All Phase N/A
G Giuseppe Marulli, MD

Robotic Assisted Major Lung Resection in Elderly Patients

The study is a retrospective observational study. The study is designed to be multicentric and it will analyze medical records from selected patients that underwent major lung resection using DaVinci surgical platform performed in the participating centers. There are no risks for the patients, as this is a retrospective data …

18 years of age All Phase N/A

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