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lung-disease Clinical Trials

A listing of lung-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,121 clinical trials
L Lauren Villeirs, MD

Prolonged Hospital Stay After Thoracoscopic Anatomical Lung Resections

In this study, the reasons for prolonged hospital stay after thoracoscopic (video- or robot-assisted) anatomical lung resections are investigated. Currently, whenever possible, these anatomical lung resections are performed thoracoscopically, as they offer significant improvements in terms of postoperative pain, number of postoperative complications, rehabilitation, tolerance for adjuvant chemotherapy, and length …

18 years of age All Phase N/A
G Giuseppe Marulli, MD

Robotic Assisted Major Lung Resection in Elderly Patients

The study is a retrospective observational study. The study is designed to be multicentric and it will analyze medical records from selected patients that underwent major lung resection using DaVinci surgical platform performed in the participating centers. There are no risks for the patients, as this is a retrospective data …

18 years of age All Phase N/A

Bovine Reinforcement in Stomach, Colorectal and Lung Operation

The primary purpose of this prospective, randomized multicenter center study is to evaluate and compare the outcomes of stomach,colorectal and lung anastomoses reinforced with a bioabsorbable staple line reinforcement material compared with standard non-reinforced techniques with respect to the incidence of postoperative hemorrage rate, anastomotic leakage, if applicable.

18 - 75 years of age All Phase 3
J Jiayuan Sun, MD

Transthoracic vs Transbronchial Radiofrequency Ablation for Lung Cancer

The aim of this study is to investigate the efficacy and safety of transthoracic versus transbronchial ablation in the treatment of early stage peripheral lung cancer.

18 years of age All Phase N/A
Z Zhang Zhenfeng, MD, PhD

Neoadjuvant Intra-tumor Double Immunotherapy for Lung Cancer.

This phase II trial studies how well intra-tumor injection of double checkpoint inhibitors work when given alone and in combination with chemotherapy or/and bevacizumab in treating patients with previously untreated stage I-IIIA non-small cell lung cancer. Immunotherapy with monoclonal antibodies, such as ipilimumab, pembrolizumab or durvalumab, may help the body's …

18 - 75 years of age All Phase 2
T Timothy PW Fredsgaard-Jones, MBBS

Lung Innate Immunity and Microbiome After Tuberculosis Exposure

To characterise the innate pulmonary immune response and respiratory microbiome after recent exposure to M.tb and to evaluate how differences determine the outcome of M.tb exposure

18 - 65 years of age All Phase N/A
M Meng Ping Hsiao, Master

Care Needs in Lung Cancer Patients Receiving Immunotherapy

Lung cancer ranks as the leading cause of cancer-related deaths globally and is among the most common malignancies. In recent years, the advancements in immune checkpoint inhibitors have marked a significant breakthrough in the immunotherapy of lung cancer. However, immunotherapy is a relatively new treatment modality, and ongoing clinical trials …

20 years of age All Phase N/A
M Mattias Hedman, MD PhD

RealMove (Lung): Assessing Tumour Motion With Dynamic MRI

The study aims to develop an improved method to tailor the geometric safety margin when treating with stereotactic body radiotherapy (SBRT), to avoid tumour cells being missed during irradiation and to limit the exposure of normal tissues as much as possible. Dynamic magnetic resonance imaging (MRI) is assumed to represent …

18 years of age All Phase N/A
E Elisabeth Taucher, Dr. Dr.

EXERCISE AND THE IMMUNE RESPONSE IN LUNG CANCER

This project is about the effect of a 12-week training therapy intervention in patients suffering from non-small cell and small-cell lung cancer. It has widely been accepted that exercise is preventive against certain types of cancer. Individuals following an active lifestyle have a significantly lower risk for several chronic diseases, …

18 - 75 years of age All Phase N/A
C Chandra Bortolotto, MD

Magnetic Resonance Imaging of the Lung: Oncological Applications

Lung neoplasms are characterized by a complex interaction between tumor cells and a variety of resident and infiltrating host elements, secreted factors, and extracellular matrix proteins, collectively referred to as the microenvironment. Nowadays, in the setting of lung cancer, and in particular non-small cell lung cancer (NSCLC), the evaluation of …

18 years of age All Phase N/A

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