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heart-failure Clinical Trials

A listing of heart-failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 852 clinical trials

SGLT2 for Heart Failure in CHD Patients

Heart failure (HF) in adult patients with congenital heart disease is a major cause of morbidity and mortality. Approximately 30% of patients with significant congenital heart disease will develop signs of heart failure. Heart failure leads to hospitalization and disability with a longer hospital stay and higher health care costs …

18 years of age All Phase N/A
C Carlo Pappone, MD, PhD

Acute Response to Left Bundle Branch Area Pacing With SyncAV

This clinical investigation is a prospective, single-arm, post-market, non-randomized, single-center study designed to evaluate the effectiveness of the SyncAV CRT dynamic atrioventricular (AV) delay feature when used with left bundle branch area pacing (LBBAP).

18 years of age All Phase N/A
g gulsen akcay, ass. prof.

MAP( Mean Arterial Pressure) and Mortality Relation in Patients With Heart Failure

Aim of this observational study is to evaluate the relationship between mean arterial pressure (MAP) and mortality in patients presenting to the emergency department with acute heart failure, focusing on emergency department monitoring and subgroup presentations. Our goal is to determine the impact of subgroup characteristics on mortality among patients …

18 years of age All Phase N/A

Voice Analysis for Monitoring Patients With Heart Failure

This observational study involves ADHF patients at two sites in the United States and Germany. After informed consent and screening assessments, participants will perform daily voice recordings during their hospital stay, from admission until discharge. Alongside voice data, additional clinical information such as left ventricular ejection fraction, NTpro-BNP levels, and …

18 years of age All Phase N/A
A Anecita P Fadol, MSN,PHD,RN

Symptom Burden and Health Related Quality of Life of Cancer Patients With Concurrent Heart Failure

To describe and compare the symptom burden in cancer patients with concurrent diagnosis of heart failure (HFrEF compared to HFpEF).

18 years of age All Phase N/A
D Daniele Masarone Dr.

CCM and Implementation of Guideline-Directed Medical Therapy in Patients With Heart Failure (Fix-GDMT-HF)

The primary objective of this study is to evaluate the impact of Cardiac Contractility Modulation (CCM) therapy on the initiation and up-titration of Guideline-Directed Medical Therapy (GDMT) in patients with heart failure (HF). This will be assessed by the change in Quad Medication Score (QMS) from baseline (pre-CCM) to 6-month …

18 years of age All Phase N/A
V Vojtech Melenovsky, MD, PhD

Metabolic Response to the Initiation of Heart Failure Therapy

This protocol is a component of the CarDia project under the National Institute for Metabolic and Cardiovascular Disease Research (EXCELES Program, ID: LX22NPO5104), which is financed by the European Union - Next Generation EU. It falls under Work Package 5 (WP5), focusing on metabolic disorders in heart failure. The aim …

18 years of age All Phase N/A

A Study of Paramedic HF Management

The purpose of this research is to see if having community paramedic (CP) visit patients at home to manage their heart failure help them stay out of the hospital and improve their overall health compared to standard care. The investigators want to find out if their approach is better for …

18 years of age All Phase N/A
J Jennifer L Conway, MD, MSc

WeRoaM: Wearable Remote Monitoring in Heart Failure

Remote physiologic monitoring (RPM) of heart failure (HF) patients with a virtual platform is well established in adult care. However, this technology remains untested in pediatrics and care continues to rely on a hospital-based model which presents challenges in providing equitable access to care for those with lower socio-economic status …

8 - 18 years of age All Phase N/A

Impella Pump Return Study to Analyze Deposits and Biomaterial in Used Pumps

Analysis of cell and protein deposits on the Impella Heart Pump.

18 years of age All Phase N/A

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