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heart-failure Clinical Trials

A listing of heart-failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 845 clinical trials
K Krishnaraj Rathod, MBBS, PhD

Cardio-Renal Registry

Cardiovascular disease is the leading cause of morbidity and mortality among patients with chronic kidney disease (CKD). Even after adjustment for known cardiovascular risk factors, including diabetes and hypertension, mortality risk progressively increases with worsening CKD. As glomerular filtration rate (GFR) declines the probability of developing coronary artery disease (CAD) …

16 years of age All Phase N/A
V Vladimir Rudnov, MD

The Role of Concomitant Diseases in Postoperative Complications Risk Stratification.

Study is conducted to assess the prevalence and structure of comorbidity among patients undergoing abdominal surgery and produce the stratification of the risk of postoperative complications by identifying independent predictors for its development.

18 years of age All Phase N/A
S Samuel Cote, RRT

Right Ventricular Pressure Waveform Monitoring in Cardiac Surgery

RV dysfunction has been associated with increased mortality in the ICU and cardiac surgical patients. Thus, early identification of RV dysfunction at less severe stages will allow for earlier intervention and potentially better patient outcomes. However, so far, no studies have reported prospectively the prevalence of abnormal RV pressure waveform …

18 years of age All Phase N/A
B Bella Clinical Research Coordinator

Cholate Clearance in Fontan and Heart Failure

The goal of this study is to use the HepQuant dual cholate clearance assay, which has been shown to measure liver function in people with known chronic liver conditions, to assess severity of Fontan-associated liver disease (FALD). This study aims to understand the role impaired blood flow to the liver …

18 years of age All Phase N/A
S Steven Hsu

Hemodynamic Assessment of underLying myocyTe Function in Right Heart Failure

Right ventricular (RV) failure is recognized to worsen patient outcomes in the setting of heart failure with reduced ejection fraction (HFrEF)-related pulmonary hypertension (PH), yet the investigators fall short in trying to identify and treat it. The current proposal will (1) determine the best clinical indicators of intrinsic RV myocyte …

18 - 90 years of age All Phase N/A
S Sarah Charman

Lifestyle Behaviours of Women Newly Diagnosed With Heart Failure

Heart Failure occurs when the heart's ability to pump blood is reduced. Heart failure can lead to symptoms of breathlessness, fatigue and ankle swelling, and result in health complications including damage to other organs (e.g. kidneys), reduced function and quality of life. Although the symptoms of heart failure are similar …

18 years of age Female Phase N/A

Cardiac Hemodynamics During Left Ventricular Assist

The goal of this observational study is to exploratively investigate intracardiac geometry and hemodynamics in patients with ongoing HeartMate 3-therapy in the Swedish Southeast Healthcare region. The main question it aims to answer is: How do different flow levels in the HeartMate 3 left ventricular assist system influence intracardiac geometry …

18 years of age All Phase N/A
M Manuel Wilbring

Aeson TAH System - Post-Market Clinical Follow-up Study

The safety and performance of the Aeson TAH system have been demonstrated for the CE mark approval in December 2020. The purpose of this post-market clinical investigation is to confirm the safety, performance and effectiveness of the Aeson TAH system when used in routine care by surgeons.

18 years of age All Phase N/A
D Desana Thayaparan, BSc

Predicting Readmissions Using Omics, Biostatistical Evaluate and Artificial Intelligence

This study is a prospective registry that aims to predict readmissions in patients with heart failure, using -omics, machine learning, patient reported outcomes, clinical data and other high-dimensional data sources.

18 - 105 years of age All Phase N/A
A Aayla Jamil, MBBS MPH

Cardiopulmonary Stress Testing (CPET) AlloSure Study

Cell-free DNA does not vary significantly as a function of the activity of immunologically quiescent cardiac transplant recipients, despite the metabolic demands of the transplanted organ. (The implication of the null result would be that no restrictions to patient activity, nor modification of cardiac rehabilitation prescription, would be necessary to …

18 years of age All Phase N/A

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