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Seizure Disorders Clinical Trials

A listing of Seizure Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 338 clinical trials

Implementation and Cost Evaluation of Project UPLIFT

This study tests Project Using Practice and Learning to Increase Favorable Thoughts (UPLIFT) which is a Mindfulness-based Cognitive Behavioral Therapy program teaching participants with epilepsy methods that include challenging thoughts, behavioral activation, coping, problem-solving, and mindfulness, for well-being and costs. Project UPLIFT is delivered as weekly sessions over 8 weeks.

18 years of age All Phase N/A
B Bruna de Souza, Research Coordinator

A Clinical Trial of PRAX-222 in Pediatric Participants With Early Onset SCN2A Developmental and Epileptic Encephalopathy

The goal of this trial is to learn about the effect of PRAX-222 in pediatric participants with early onset SCN2A developmental and epileptic encephalopathy (DEE), aged 2 to 18 years.

2 - 18 years of age All Phase 1/2

Percutaneous Repair for Drug - Resistant Epilepsy by Intervention of Closing the Patent Foramen Ovale(PREDICT-PFO Trial)

Patent foramen ovale (PFO) is the most common cause of right-to-left shunt (RLS) in the adult heart, with a prevalence of approximately 25% in the general population. Extensive research has demonstrated an association between PFO and neurological conditions such as cryptogenic stroke, migraine, and sleep apnea syndrome, and it is …

18 - 60 years of age All Phase N/A
F Faming Zhang, MD, PhD

Fecal Microbiota Transplantation for Epilepsy

Increasing evidences showed the microbiota effects on neuropsychiatric disorders. This clinical trial aims to evaluate the efficacy and safety of fecal microbiota transplantation for epilepsy.

3 - 60 years of age All Phase 2/3
K Kate Wang

Subcortical Arousal in Perceptual Awareness

The study is a multi-site study and will be conducted at up to 11 investigative sites in the United States. The study will investigate subcortical arousal circuits in visual perception using techniques with complementary strengths based on promising initial studies.

13 years of age All Phase N/A
P Paolo Federico, MD, PhD

Treating Postictal Symptoms Using Ibuprofen and Nifedipine

This study will evaluate the effect of ibuprofen or nifedipine on post-seizure hypoperfusion and neurological deficits in patients with epilepsy. One group will receive ibuprofen, another will receive nifedipine, and anther placebo.

16 years of age All Phase 2
É Élida Carneiro, PhD

Integrative and Complementary Health Practices (PICS)

Complementary medicine, considered an unconventional approach, is performed in conjunction with conventional medicine. In Brazil, Integrative and Complementary Practices in Health have been inserted by the National Ordinance of Integrative and Complementary Practices. The aim of this study is to evaluate the effects of laying on of hands with spiritual …

18 years of age All Phase N/A
B Brian K Gehlbach, MD

Carbon Dioxide (CO2) Chemosensitivity and SUDEP

The purpose of this research study is to better understand what causes Sudden Unexpected Death in Epilepsy (SUDEP). This study will enroll subjects from the University of Iowa Hospitals and Clinics (UIHC) Epilepsy Monitoring Unit (EMU) and Epilepsy Clinics. The investigators will analyze the effects of seizures on breathing, on …

18 - 99 years of age All Phase N/A
M Marcus Ng, MD

Lemborexant Treatment of Insomnia Linked to Epilepsy

The goal of this clinical trial is to assess whether Lemborexant can improve sleep in patients with epilepsy.

18 years of age All Phase 3
C Cinzia Fattore

Effect of Cognitive Behavioral Play Intervention and Epilepsy

The goal of this clinical trial is to assess the effectiveness of Cognitive Behavioral Play Therapy interventions in patients with epilepsy. Children with epilepsy will be randomly assigned to one of two intervention conditions: the experimental group will receive cognitive-behavioral play intervention, while the control group will engage in free …

6 - 10 years of age All Phase N/A

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