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pregnancy Clinical Trials

A listing of pregnancy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 826 clinical trials
A Ayesha Bryant, MD, MSPH

Exosome Cargo From Preeclampsia Patients

Although extensively studied, the cause of preeclampsia remains uncertain other than it is thought that the placenta plays a critical role in the development of preeclampsia. Recent data revealed that exosomes released from the placenta could cause preeclampsia by transporting specific cargo responsible for the pathophysiological changes associated with the …

18 - 45 years of age Female Phase N/A
A Anna Stanhewicz, PhD

Daily Aspirin Treatment After Preeclampsia

Women who develop preeclampsia during pregnancy are four times more likely to develop cardiovascular disease later in life, even if they are otherwise healthy. The reason why this occurs may be related to lasting blood vessel damage after the pregnancy but there are currently no specific treatment strategies to prevent …

18 - 50 years of age Female Phase 0
A Anna Stanhewicz, PhD

Prenatal Aspirin and Postpartum Vascular Function

Preeclampsia is a pregnancy disorder affecting \~5-10% of pregnancies in the United States. Women who develop preeclampsia during pregnancy are more likely to develop and die of cardiovascular disease later in life, even if they are otherwise healthy. The reason why this occurs is unclear but may be related to …

18 - 50 years of age Female Phase 0
G Giorgina PICCOLI

Prediction of Chronic Kidney Disease Following Pre-eclampsia: Diagnosis and Early Care

Pre-eclampsia (PE) is a pregnancy-associated syndrome of variable severity, classically defined by the combination of hypertension and proteinuria in a previously non-hypertensive or proteinuric patient. These symptoms normally resolve within 2-3 months after delivery regardless of the severity of the pre-eclampsia. Regardless of its definition, preeclampsia is associated with an …

18 years of age Female Phase N/A
A Amihai Rottenstreich, MD

Predictors of Aspirin Failure in Preeclampsia Prevention

Hypertensive disorders of pregnancy (including preeclampsia) are among the leading causes of pregnancy complications and maternal deaths worldwide. They also increase the risks to the babies. Numerous interventions have been suggested in order to reduce the rate of preeclampsia. Low-dose aspirin is the most beneficial prophylactic approach in this regard. …

18 - 45 years of age Female Phase 0
J James DeVente, MD

Physical Activity to Mitigate PreEclampsia Risk

The purpose of this study is to compare the effects of aerobic (AE), resistance (RE), and combination (AERE) exercise throughout pregnancy on selected maternal and fetal/neonatal physiological variables in women at-risk for preeclampsia. The central hypothesis of this project is that exercise will decrease severity and occurrence of preeclampsia symptoms, …

18 - 40 years of age Female Phase N/A
S Sherif Ashoush, MD

Different Regimens of Magnesium Sulphate in Patients With Severe Preeclampsia

The goal of this observational study is to learn about the effects of the different drug regimens of magnesium sulphate in treatment of (severe pre-eclampsia). This condition affects some pregnant women and raises their blood pressure. It may also cause seizures (fits). The medication (magnesium sulphate) helps to prevent seizures. …

18 years of age Female Phase N/A
L Leila Varakas

Usability Study of Gestational and Postpartum Weight Management Program

The principal aim of this study is to evaluate the usability of the Hope-D gestational and 6 months postpartum weight management program. We will evaluate the usability, functionality, and acceptability of the developed Hope-D weight management program that includes digital pathway for weight management, general or individual weight management plan …

18 - 50 years of age Female Phase N/A
O Osvaldo A Reyes, MD

Angiogenic Factors in the Conservative Management of Gestational Hypertension

Hypertensive disorders of pregnancy (HPT) are an important cause of maternal-feto-neonatal morbidity and mortality, being one of the three leading causes of maternal death in our country and in developing countries. The only cure for THE is termination of pregnancy, which ends up being a decision in which gestational age …

18 years of age Female Phase N/A
G Gunisha Kaur, BA, MD

Digital Solutions to Reduce Maternal Morbidity and Mortality in Pregnant Refugee Women

The goal of this observational study is to use digital health tracking to improve how high blood pressure and other health issues are detected in pregnant refugee women. The main questions this study aims to answer are are: Can a digital monitoring system that checks for high blood pressure in …

18 years of age Female Phase N/A

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