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pregnancy Clinical Trials

A listing of pregnancy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 831 clinical trials
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Natural History of Pregnancy and Pregnancy Outcomes in Metreleptin-Treated vs Untreated Subjects With Lipodystrophy

Background Lipodystrophy is a health problem in which the body does not have enough fat tissue. People with lipodystrophy may not make enough of the hormone leptin. Leptin regulates hunger. Low leptin levels trigger hunger. People with lipodystrophy can have many health problems. They may take a drug (metreleptin) that …

6 - 98 years of age All Phase N/A
N Nadja Siebert, MD

Pregnancy Cohort in Multiple Sclerosis (MS)

Multiple sclerosis (MS) is a common inflammatory demyelinating disorder of the central nervous system frequently affecting females in their reproductive phase of life. In this prospective observational study, we obtain data on the outcome of pregnancies in MS patients and the influence of pregnancy on clinical, laboratory and MRI parameters …

18 - 50 years of age Female Phase N/A
E Erika Bonacina, PhD

Diamine Oxidase and Adverse Pregnancy Outcomes

In normal pregnancies, blood histamine concentration remains within normal values; however, the serum histaminolytic activity is increased. Histamine is mainly produced by mast cells, platelets, basophils, neurons and enterochromatin cells, where it is stored and released when required. Reduced DAO activities have been found in high-risk pregnancies. Lower DAO activity …

18 years of age Female Phase N/A
P Priyal Fadadu

Assessment of Early Pregnancy MAB Completion

This is a prospective study to evaluate if successful completion of a medication abortion in patients with very early pregnancy can be detected with a urine pregnancy test at 2 weeks instead of 4 weeks. Additionally, the resolution of pregnancy symptoms in these patients will be characterized. Enrolled participants will …

years of age Female Phase N/A
T Tien K Le, MD

Uterine Microbiome in Recurrent Pregnancy Loss

The female genital tract microbiome may reflect female reproductive health and may be related to pregnancy outcomes. Disturbances in this microbiome may be associated with adverse reproductive outcomes. The investigators hypothesize that the endometrial and vaginal microbiome composition in women with a history of recurrent pregnancy loss are different, compared …

18 - 38 years of age Female Phase N/A
S Shaziah Hassan

Pregnancy and Postpartum CGM in GDM

Gestational diabetes (GDM) is one of the most common complications of pregnancy, and up to one third of women with GDM will have abnormal blood sugars after their pregnancy. To screen for abnormal blood sugars, standard of care is a 4-12 week postpartum oral glucose tolerance test (OGTT). However only …

18 years of age Female Phase N/A
T Terezia Pinzikova, MD, PhD

CFTR Modulators in Pregnancy and Postpartum

Observational study on women with Cystic Fibrosis treated with CFTR modulators during pregnancy and postpartum and their children. Registration on maternal health parameters and effects of CFTR-modulators in the newborn infant as well as effects of exposure through mother's own milk.

- 50 years of age All Phase N/A
M Mohamed Swefy, Lecturer

Role of Cerebroplacental Ratio Discordance at 16-20 Weeks in Predicting Monochorionic Twin Pregnancies' Specific Complications

The purpose of this study is to evaluate the predictive value of CPR discordance at 16-20 weeks in MCDA twin pregnancies in predicting monochorionic-specific complications such as TTTS, TAPS, sFGR and IUFD of one or both fetuses

years of age Female Phase N/A

Impact of the Microbiome on Time to Pregnancy and Pregnancy Outcomes in Fertile Women Attempting to Conceive

This study aims to investigate the microbiome of women with previously proven fertility who plan to become pregnant.

18 - 40 years of age Female Phase N/A
A Ayushi D Balan, BA, BS

Pregnancy Registry, Infants, Serum/Milk Analysis (PRISMA)

PRISMA, is a pregnancy registry study, focused on comprehensively collecting information about pregnancy in women with chronic neurological conditions from across the United States and internationally. Depending on their specific condition (MS, CIS, NMOSD, or other) and their specific treatment, participants will be asked to contribute to different aspects of …

18 - 64 years of age Female Phase N/A

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