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Osteoarthritis Clinical Trials

A listing of Osteoarthritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 515 clinical trials
M Maria Chiara Vulpiani

Hyaluronic Acid and Adelmidrol (Hyadrol®) in Patients With Degenerative Joint Disease

Osteoarthritis is a major cause of chronic musculoskeletal pain. Behind this disorder there is a process of chronic neuroinflammation due to the overactivation of mast cells at the tissue level. The mast cells present in the synovial membranes act as first sensors in pathological situations, degranulating in an uncontrolled manner. …

40 years of age All Phase N/A

Effects of Rigid Taping in Acromioclavicular Joint Degeneration

This study will examine whether rigid taping applied to the acromioclavicular (AC) joint can reduce shoulder pain and improve shoulder function in people with AC joint degeneration. Participants with shoulder pain and a confirmed diagnosis of AC joint degeneration will be randomly assigned to one of two groups: (1) rigid …

18 - 65 years of age All Phase N/A
T Taj-Jamal Andrews

Safety and Effectiveness of the HIT Reverse HRS

The purpose of this study is to determine if the use of the HIT Reverse Hip Replacement System is safe and effective in patients undergoing total hip replacement. We will determine whether it is safe and effective by comparing it to the control devices.

50 - 75 years of age All Phase N/A
A Alexandra GIULIANI

Evaluation of the Efficacy of an Intra-articular Injection of Autologous Microfat Combined With Autologous Platelet-enriched Plasma in the Treatment of Radiocarpal Osteoarthritis: a Randomized Controlled Non-inferiority Trial Versus Total Wrist Denervation (Established Standard Treatment).

This is a phase II, prospective, comparative, randomized, single-center, open-label, parallel-group therapeutic trial. It is a non-inferiority trial to establish the efficacy of intra-articular injection of autologous microfat and PRP at the wrist in patients suffering from radiocarpal osteoarthritis in reference to wrist denervation.

18 years of age All Phase 2
D Dr. G Pagdin, MD

The Combined Use of PRP With Lipoaspirate and/or Bone Marrow Aspirate in Osteoarthritis

To demonstrate the efficacy of the combined use of platelet-rich plasma (PRP) with lipoaspirate and/or bone marrow aspirate in osteoarthritis of major joints, and to compare the outcomes achieved using three combinations: PRP plus lipoaspirate, PRP plus bone marrow aspirate, and PRP plus both lipoaspirate and bone marrow aspirate.

19 - 79 years of age All Phase 2
M Min Jung

Transcatheter Arterial Micro-Embolization (TAME) Using Nexsphere-F in Patients With Chronic Pain in Elbow or Wrist

In patients with chronic elbow or wrist pain, the pain is controlled by conventional conservative therapy The pain reduction effect of Nexsphere-F embolization in patients who need additional treatment It is intended to demonstrate safety.

19 - 80 years of age All Phase N/A
M Melissa Butcher

Stem Cell Study in Osteoarthritis of the Knee and Hip Joints

The purpose of this trial is to compare the effect of a single intra-articular injection of Lipoaspirate Concentrate vs Bone Marrow Aspirate on pain reduction and functional improvement in the treatment of the knee and hip OA.

18 - 95 years of age All Phase 2
B Beyza Afşin Bener, Medical Doctor

Effect of Genicular Nerve Block on Proprioception in Knee Osteoarthritis

The study was conducted to investigate the effect of genicular nerve block on pain, quality of life, and proprioception, which are already diminished due to the impact of osteoarthritis in individuals with knee osteoarthritis. Does genicular nerve block reduce pain and improve the quality of life in patients with knee …

55 - 75 years of age All Phase N/A

ARVIS TKA vs Conventional TKA

This study is a pilot analysis of a novel augmented reality guidance platform, the augmented reality visualization and information system (ARVIS, Insight Medical), with aims to demonstrate accuracy of bone resection and implant alignment during kinematic alignment total knee arthroplasty.

18 years of age All Phase N/A
L Laetitia Garcia, Msc

Physical Activity Promotion in Osteoarthritis Patients

The main purpose of this project is to promote physical activity in patients with osteoarthritis. More specifically, this study aims to test the acceptability of an app to promote physical activity in the target population, and consequently the feasibility of such an approach. A mobile phone application - namely PIANISSIMO …

18 years of age All Phase N/A

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