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Osteoarthritis Clinical Trials

A listing of Osteoarthritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 536 clinical trials
M Monica Guma, MD

Effect of Anti-inflammatory (ITIS) Diet in Knee Osteoarthritis

To study the effect of anti-inflammatory diet on clinical and biological outcomes in patients with knee osteoarthritis

18 years of age All Phase N/A
J Jérémie Sellam, Md PhD PU-PH

Efficacy of Surgical Joint Denervation in Painful Digital Osteoarthritis

Digital osteoarthritis is the second localization of symptomatic osteoarthritis, after the knee. Its cardinal symptoms are particularly intense pain and functional impairment in the case of the erosive form. There is currently no etiological treatment for osteoarthritis. Symptomatic treatments have a modest efficacy, which justifies the search for new treatments. …

18 years of age All Phase N/A
M Moustafa Ismail, Assistant Professor

Management of Combined Patellofemoral and Medial Compartment Knee Osteoarthritis

Evaluate the results of management of patients with patellofemoral and medial compartment knee osteoarthritis with open wedge high tibial osteotomy with or without arthroscopic partial lateral patellar facetectomy

35 - 60 years of age All Phase N/A
J Josie Morris, Bsc

Movement Dynamics of Knee Osteoarthritis and Total Knee Replacement

This research aims to explore differences in walking and functional movement mechanics, exercise response, and physical activity between people with osteoarthritis (OA), those who have undergone total joint replacement, and healthy individuals.

40 - 85 years of age All Phase N/A
S Siobhan Scharbun, BSc

Transcranial Direct Current Stimulation and Yoga for Knee Osteoarthritis

People with knee arthritis often experience constant pain, and current treatments aren't very effective. This can lead to limited movement and more health problems. Knee arthritis is a big part of healthcare costs in Canada, and its pain is a major reason people see doctors. The pain is linked to …

45 years of age All Phase N/A
H Hira Shaukat, TDPT

Effects of Voodoo Flossing Technique in Knee Osteoarthritis Patients

Knee osteoarthritis (KOA) is a prevalent degenerative joint disease characterized by pain, stiffness, and reduced physical function, significantly impacting quality of life especially in elderly population. This study aims to evaluating the effectiveness of an emerging technique, known as 'Voodoo Flossing' on pain, range of motion and physical function in …

45 - 65 years of age All Phase N/A
M Mahdi Qadir, PhD

Knee Osteoarthritis Rehab: High-Intensity Laser vs Classical Modalities

This study aims to compare the effectiveness and safety of High-Intensity Laser Therapy (HILT) with conventional physical therapy treatments in patients with knee osteoarthritis. Knee osteoarthritis is a common condition, especially in older adults, causing pain, stiffness, reduced movement, and difficulty performing daily activities. Current treatments focus on reducing pain …

30 - 60 years of age All Phase N/A
N Nadide Koca, M.D.

Perineural Dextrose Versus Local Anesthetic Injections in Knee Osteoarthritis

This prospective observational study aims to compare the clinical effectiveness of perineural 5% dextrose injections and perineural local anesthetic injections in patients with symptomatic knee osteoarthritis. Adult patients receiving routine perineural injection therapy will be followed for six months. Pain intensity and functional outcomes will be assessed at baseline and …

40 - 65 years of age All Phase N/A
D Dr. David Wasserstein

Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR)

The goal of this clinical trial is to see if people with knee osteoarthritis would be willing to comply and adhere to incorporating Recombinant Human Growth Hormone (rHGH), specifically Saizen Somatropin solution, into their treatment plan. Participants will be asked to: Self-inject the treatment solution (placebo or somatropin) into the …

18 - 65 years of age All Phase 1/2

Effect of Structured Exercise in Patients With Knee Osteoarthritis

The aim of this randomized controlled trial is to evaluate the effect of Nordic walking and inspiratory muscle training (IMT) on cardiopulmonary function in patients with knee osteoarthritis (OA). Mild-to-moderate knee OA patients are randomly allocated into Experimental group (Nordic walking plus routine management) or Control group (Routine management). While …

55 years of age All Phase N/A

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