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Osteoarthritis Clinical Trials

A listing of Osteoarthritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 536 clinical trials
G Guanghua Lei, Prof.

L-arginine for Knee Osteoarthritis Patients

This study will examine the pain-relief efficacy and safety of L-arginine in knee OA patients.

40 - 80 years of age All Phase N/A
S Sherwood Alexis, MHA, MBA

Remote Tai Chi for Knee Osteoarthritis

The goal of this pragmatic randomized trial is to evaluate the effectiveness of remote Tai Chi to treat knee pain in adults with knee osteoarthritis. The main questions the trial aims to answer are: Compared to routine care, will patients with Knee OA receiving remote Tai Chi exhibit greater improvement …

50 - 100 years of age All Phase N/A
P Pavol Vigláš

Percutaneous Transcatheter Genicular Embolization in Osteoarthritis

This clinical study investigates a minimally invasive treatment called percutaneous transcatheter embolization of knee arteries for patients with chronic knee pain caused by advanced knee osteoarthritis or persistent pain after total knee replacement. Osteoarthritis of the knee is a common degenerative condition that can lead to long-term pain, reduced mobility, …

40 - 80 years of age All Phase N/A
K Katie Boncella

Knee Osteoarthritis Rehabilitation Through Rotational Inertia

This study is testing whether a new type of exercise program, called eccentric overload training using a flywheel device, can improve stair-climbing ability in people with knee osteoarthritis. The flywheel device provides resistance throughout the entire movement and gives extra challenge during the muscle-lengthening phase of exercise. This type of …

40 - 70 years of age All Phase N/A
N Nienke Willigenburg, PhD

Migration in Total Hip Arthroplasty with a Cemented BiMobile Cup: Better Stability with More Cement?

Objective: The main objective of this study is to compare the (early) migration of the cemented BiMobile cup at two year post-surgery between two different cup sizes after standard optimal reaming, and consequently adjusting the cement mantle into circa 2 or 4 mm, in patients with a primary cemented total …

65 years of age All Phase N/A
C Christine Pellegrini

Dose Response of Exercise for Arthritis Management

The purpose of the study is to see examine the effects of 3 different levels of physical activity (45 minutes/week, 90 minutes/week, or 150 minutes/week) on arthritis symptoms.

18 years of age All Phase N/A
X Xiaojuan Li, PhD

Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry

Currently the diagnosis of OA is based on radiographs and clinical findings, which is limited to detecting late-stage disease. There is a pressing, unmet clinical need for robust assessment of early changes in cartilage health. Towards this goal, extensive efforts are ongoing to develop quantitative MRI for cartilage matrix analysis. …

18 - 50 years of age All Phase N/A

Hydrogel Assessment for Local Treatment of Osteoarthritis

The study aims to evaluate the safety and tolerability of one intra-articular injection of Hydrogel OA 2% for the symptomatic treatment of osteoarthritis of the knee.

35 - 75 years of age All Phase N/A
M Mark W Little, MD

Genicular Artery Embolisation for Knee Osteoarthritis II

This clinical study is designed as a double-blind sham controlled randomised trial with the option of sham group crossover to receive the GAE treatment at 6 months after unblinding. This study will determine if embolisation of abnormal neovasculature arising from branches of the genicular arteries reduces pain in patients with …

45 years of age All Phase N/A
K Kasper Staberg Madsen, MD

Metformin Treatment of Patients with Hand Osteoarthritis

To compare metformin (2 g daily), or maximum tolerated dose, for 16 weeks with placebo as a treatment of hand osteoarthritis symptoms.

18 years of age All Phase 3

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