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Osteoarthritis Clinical Trials

A listing of Osteoarthritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 515 clinical trials
G Graeme Witte

Brain-Based and Clinical Phenotyping of Pain Pharmacotherapy in Knee Osteoarthritis

This is a clinical trial of people who have pain due to knee osteoarthritis at Northwestern University Feinberg School of Medicine. The study will last for about 20 weeks. 180 qualified participants will be randomly assigned in a 1:1:1 ratio (60 participants per group) to one of three treatment groups: …

41 years of age All Phase 4
J James Ellsmere, MD

Optimal Management of Extreme Obesity and Severe Knee Osteoarthritis Feasibility Trial

Does weight loss surgery in patients with morbid obesity prior to knee replacement surgery improve outcomes from knee replacement surgery

18 - 65 years of age All Phase N/A
K KINZA ANWAR, MS-OMPT

Bowen Technique With Retro-walking on Hamstring Flexibility in Knee Osteoarthritis

The aim of this randomized controlled trial is to find the effects of Bowen technique with retro-walking on hamstring flexibility, pain, dynamic mobility and knee related disability in knee Osteoarthritis patients

40 - 60 years of age All Phase N/A
M Marc SAPOVAL, MD

Effect of Genicular Arteries Embolization in Symptomatic Knee Osteoarthritis LipioJoint-2

Knee OsteoArthritis (KOA) is a common disease associated with pain and impaired function. Many patients are not relieved of their symptoms with enough efficacy by conservative treatments. Genicular Arteries Embolization (GAE) is a new minimally invasive endovascular treatment allowing symptoms relief. The investigator previously demonstrated the safety of GAE using …

40 - 90 years of age All Phase 3
P Paul N. M. Lohle

Study in Patients With Knee Osteoarthritis Treated by Embolization Using NBGM200

Study in patients with knee osteoarthritis treated by embolization using NBGM200

50 years of age All Phase N/A
A Andrea Niklasson, M.D.

Promoting Sleep to Alleviate Pain - Arthroplasty

PROSAP-A is a perioperative randomized, controlled trial with a 12-month follow-up period after total knee arthroplasty (TKA) or total hip arthroplasty (THA), aiming to investigate both acute and long-term postoperative effects of preoperative sleep-promotion. Participants with clinically significant insomnia symptoms will be randomized to a brief, hybrid version of cognitive …

18 - 100 years of age All Phase N/A
S Scott D Uhlrich, PhD

Effects of Movement Retraining on Knee Loading in Individuals With Knee Osteoarthritis

This study investigates how well individuals with knee osteoarthritis can learn to alter their calf muscle activation using haptic biofeedback while walking and evaluates how these changes affect knee loading. Prior research has utilized musculoskeletal simulations to determine that reducing the activation of one of the calf muscles, the gastrocnemius, …

18 years of age All Phase N/A
K Kosaku Aoyagi, PhD

Upper and Lower Extremity Exercise and Exercise-Induced Hypoalgesia in Knee Osteoarthritis

The objective of the study is to explore the effects of arm exercise (UE, arm ergometer) vs. leg exercise (LE, cycling ergometer) on exercise-induced hypoalgesia (EIH), central pain mechanisms and knee pain in people with knee osteoarthritis (OA). Furthermore, we will explore relations of socioeconomic status, racial discrimination, acculturative stress, …

45 - 90 years of age All Phase N/A
M Meng-Huang Wu

MRgFUS and RFA for Treatment of Facet-joint Osteoarthritis Low Back Pain

This is a prospective, randomized, two-arm, phase II study. The purpose of this study is: To evaluate and compare the efficacy and safety of magnetic resonance-guided focused ultrasound (MRgFUS) and radiofrequency ablation (RFA) for treatment of facet-joint osteoarthritis low back pain. Determining the effect of the MRgFUS System and RFA …

20 - 79 years of age All Phase N/A
R Ralph Ortiz, DO

Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to Osteoarthritis

The purpose of this study is to assess the ability of long-duration low intensity therapeutic ultrasound (LITUS) to alleviate knee Osteoarthritis pain over a 24-week period. The primary objective of this study is to evaluate the analgesic effect of LITUS in subjects suffering from knee Osteoarthritis pain. Secondary objectives are …

50 - 85 years of age All Phase 2

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