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Vaccination Clinical Trials

A listing of Vaccination medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 118 clinical trials
L Lisa Anderson

TLR-9 Adjuvanted Vaccination for Chronic Hepatitis B

The goal of this clinical trial is to learn if HEPLISAV-B, a vaccine that is approved to prevent hepatitis B infection in people that are not already infected, is safe in people already chronically infected with hepatitis B. The main quiestions it aims to answer are: Is HEPLISAV-B safe in …

18 years of age All Phase 1
S Sylvia Bähring, PD Dr.

VITAL: Vaccination, Immunity, Time-restricted Eating, Aging and Lifestyle

The aim of this study is to investigate the effects of a four-week time-restricted eating (TRE) intervention on autophagy, immune function, and vaccine response to a seasonal influenza and COVID-19 vaccines in older healthy subjects.

60 - 85 years of age All Phase N/A
P Paola Cicconi, MD

Combination Vaccination and Broadly Neutralising Antibody Therapy in HIV

The goal of this observational study is to learn about the 6-month effects of Levator Resection combined with Fascial Sheath Suspension surgery in patients who undergo this procedure to treat congenital ptosis. The main questions it aims to answer are: Does this combined surgery improve best-corrected visual acuity, stereopsis, and …

18 - 64 years of age All Phase 2
F Fabien Taieb, MD

Description of the Immune Response to Yellow Fever Vaccination

Vaccine protection depends on a specific adaptive immune memory. However, a little-explored aspect of certain live vaccines may provide beneficial, non-specific protection against infections or pathogens other than the one from which the vaccine is derived. This is the concept of innate immune memory or " trained immunity", which differs …

18 - 65 years of age All Phase N/A
J Jamie Mills, BS, CCRC

Characterizing the Human Airway Immune Response to FluMist Vaccination

The goal of this clinical trial is to measure the immune response in the blood, nose, and lungs after participants receive either the FDA-approved inactivated influenza vaccine or the FDA-approved intranasal FluMist vaccine. The study will evaluate immune responses in groups of healthy, non-pregnant, volunteers between the ages of 18 …

18 - 40 years of age All Phase 4
Z Zhang Zhenfeng, MD, PhD

Anti-cancer DC Cell Vaccination to Treat Solid Tumors

Placental or tumor-derived heat shock protein gp96 is collected, purified, and stored. The DC cells are isolated from the patient's blood and then cocultured with the gp96 to obtain the activated DC cell product. The manufactured DC cells are subcutaneously or intra-tumor injected into the patient. Clinical studies will be …

18 - 80 years of age All Phase 1
M Michael Churnetski

Evaluation of Human Immune Responses Vaccination in Patients With Lymphoma

This clinical trial evaluates the influenza virus vaccination in evaluating human immune response in patients with lymphoma. Evaluating immune response may increase the understanding of how the immune system changes when patients receive treatment for lymphomas by looking at the antibody levels and the level of the different cells that …

18 years of age All Phase N/A
J Jessica Wells, PhD

Advancing HPV Vaccination Among HIV Positive Adults: The CHAMPS Study

People living with HIV (PLWH) are 28 times more likely to be diagnosed with Human Papillomavirus (HPV) - associated anal cancer than the general population. The HPV vaccine is an effective and safe approach to prevent and reduce the risk of HPV-related disease among PLWH. HPV vaccine programs tailored and …

18 - 45 years of age All Phase N/A

SARS Cov 2 Vaccination in Adolescents With Juvenile Idiopathic Arthritis

Since june 2021, vaccination against the SARS-Cov2 virus is recommanded in France to all children from 12 to 18 years old. In the specific population of teenagers living with juvenile arthritis, the vaccine seems to be safe and well tolerated. It has been shown previously that this population has a …

12 - 18 years of age All Phase N/A
S Sigrun Einarsdottir, MD, PhD

Vaccination Against Human Papillomavirus (HPV) After Allogeneic Stem Cell Transplantation

Patients who undergo allogeneic stem cell transplantation lose previously acquired immunity and are routinely revaccinated against many infectious diseases. For several reasons, these patients have a long-term immune deficiency due to the transplant itself (lack of immune reconstitution) and due to possible complications, primarily GvHD and its treatment. The risk …

18 - 45 years of age All Phase 2

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