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Nicotinamide Clinical Trials

A listing of Nicotinamide medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 37 clinical trials
M Min Shi

Nicotinamide Riboside in Ulcerative Colitis

This is a randomized, double-blind pilot study of Nicotinamide Riboside (NR) in Pediatric-onset Ulcerative Colitis (UC).

- 18 years of age All Phase N/A
K Kamoly Dorneles

Nicotinamide Riboside Clinical Trial for GWI

In this multi-site trial, we will use a randomized, double-blind, placebo-controlled study design to test whether 300 mg of Nicotinamide Riboside (NR) can achieve the primary objective of increasing plasma NAD+ levels in participants with Gulf War Illness (GWI).

47 - 70 years of age All Phase N/A
D Dalia Abdelmohsen, Professor

The Effect of Nicotinamide on the Clinical Outcome of Rheumatoid Arthritis Patients

A randomized controlled interventional study to evaluate the efficacy and safety of nicotinamide supplementation in rheumatoid arthritis patients receiving conventional synthetic disease modifying anti-rheumatic drugs.

18 - 65 years of age All Phase 2
R Ramratan R Sharma, PhD MHSA

Impacts of Nicotinamide Riboside on Functional Capacity and Muscle Physiology in Older Veterans

Frailty is an age-associated clinical condition of poor physiological reserve that increases risks for falls, hospitalization and mortality. Nicotinamide adenine dinucleotide (NAD) is a critical co-factor needed for many cellular processes. The natural levels of NAD decline aging and this has been linked to physical performance decline in animals. Human …

65 - 85 years of age All Phase N/A
K Katarina Lundervold

NADream: Effects of Nicotinamide Adenine Dinucleotide Supplementation on Sleep Quality in Healthy Individuals

The purpose of this study is to evalue the effects of nicotinamide adenine dinucleotide (NAD) supplementation (nicotinamide riboside (NR) form) on sleep in healthy adults compared to a placebo. NAD is important for brain health and energy balance and a proposed explanation for its effect on sleep is that NAD …

40 - 60 years of age All Phase 2
B Beier Jiang

Quzhou Population Cohort Research Project (Aging Related Research: Intervention of Nicotinamide Mononucleotide in Middle-aged and Elderly People)

This study is a single center, randomized, double-blind, placebo-controlled clinical trial of drug intervention on aging. The purpose is to explore the effectiveness of NMN on the premise of ensuring the safety of oral drug, in order to provide effective intervention means for delaying aging and improve the quality of …

40 - 70 years of age All Phase N/A

The Glaucoma Nicotinamide Trial

The Glaucoma Nicotinamide Trial (TGNT) is a prospective, randomized, placebo-controlled double-masked clinical trial composed of two cohorts; The Swedish Glaucoma Nicotinamide Trial (SGNT) and the Vitamin B3 In Glaucoma Study (VBIGS). Patients with open-angle glaucoma (OAG) will be randomized to receive either Nicotinamide or placebo through block randomization stratified by …

18 years of age All Phase N/A
K Kjell-Morten Myhr

Nicotinamide Riboside Supplementation In Progressive Multiple Sclerosis

The purpose of this study is to assess the safety and efficacy of Nicotinamide riboside (NR) for treatment of patients with progressive multiple sclerosis. The main question it aims to answer is: • Does NR delay disability progression in progressive multiple sclerosis? Participants will be treated with NR or placebo …

18 - 65 years of age All Phase 2
S STEFANIE WHITE, CCRP

Protective Effect of Nicotinamide Riboside Against Acetaminophen Toxicity

Over-the-counter drugs like acetaminophen (e.g., Tylenol®) can be detrimental. In space, astronauts who have pain and constant discomfort use acetaminophen extensively. Investigators are studying the effects of acetaminophen under space-like conditions since acetaminophen might affect astronauts' health. Investigators also wish to see whether a dietary supplement can reduce some negative …

18 years of age All Phase 1

Benefits of Nicotinamide Riboside Upon Cognition and Sleep

Poor sleep quality and short sleep duration may be a mechanistic component of cognitive impairment in older adults, associated with a decline in brain-derived neurotrophic factor. Increasing the availability of nicotinamide adenine dinucleotide (NAD+) with supplementation of its precursor, nicotinamide riboside (NR), a form of vitamin B3 may increase the …

65 - 85 years of age All Phase N/A

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