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Found 228 clinical trials
H Heberto J Suarez-Roca, MD, PhD

Carotid Sinus Massage in Trendelenburg Position for Headache Relief

Headaches significantly impact patients' quality of life, with tension-type headaches and migraines being among the most prevalent types. There is growing evidence suggesting that blood pressure regulation and baroreceptor activity play a role in headache pathophysiology. Carotid sinus massage (CSM), particularly when combined with the modified Trendelenburg position, may modulate …

16 years of age All Phase N/A
A Anna Anselmo, Study Principal Investigator

PERSONOLOGICAL STRUCTURE, COGNITIVE FUNCTIONS AND CENTRAL SENSITIZATION IN HEADACHE

Headache, in its episodic and chronic forms, cannot be considered solely as an isolated neurological symptom, but as a complex condition of a bio-psycho-social nature. While in the episodic form the painful episodes occur intermittently and have a variable impact on daily life, in the chronic form the disease evolves …

18 - 60 years of age All Phase N/A
R Rola a AlHabashneh, Prof

Effect of Injectable Hyaluronic Acid (HYADENT BG (HA)) on Bone Healing in Extraction Sockets

Complications such as postoperative pain and delayed socket healing are relatively common following surgical extraction of mandibular third molars. Various biomaterials have been investigated to enhance wound healing and reduce postoperative morbidity. Hyaluronic acid (HA) has demonstrated anti-inflammatory and regenerative properties that may improve both soft and hard tissue healing. …

18 - 35 years of age All Phase N/A
K Kai O. Kaye, Dr.

Study of RRS® HA Long Lasting for Improving Facial Wrinkles and Skin Quality

The objective of this clinical study is to confirm the clinical performance and long-term safety of the CE-marked RRS® HA Long Lasting in the treatment of skin photoaging and its consequences, with a primary focus on improving facial wrinkles and skin quality in healthy adults. The main questions it aims …

18 years of age All Phase N/A
C Chumgyili Li

Investigating the Impact of Acupuncture on the Quality of Life of Primitive Headaches Patients

Primary headache is one of the most common neurological diseases in modern society, which seriously affects the patient's quality of life. Although the use of painkillers can alleviate primary headache symptoms, it may also cause drug dependence. Therefore, alternative therapies that do not rely on drugs have attracted increasing attention …

18 years of age All Phase N/A

Efficacy of Therapy With PRP Injections Versus HA in Patients With Advanced Grade of GONArthrosis

Gonarthrosis is a chronic pathology affecting the knee joint and tissues. It is characterized by progressive degeneration of articular cartilage, bone and surrounding structures. Diagnosis is based on clinical, biological and radiological criteria. When knee osteoarthritis becomes symptomatic, it leads to pain associated with stiffness and functional discomfort, impacting on …

18 years of age All Phase N/A
L Laleh Zarrinkoob, MD, PhD

Pathophysiological Mechanisms and Implication of Treatment in Postural Puncture Headache

To improve treatment for post dural puncture headache, its pathophysiology needs to be explored. Dural puncture alters CNS dynamics; using advanced MRI, we aim to investigate PDPHs pathophysiology explained by brain movement, cerebral blood flow, CSF dynamics and the effect of epidural blood patch.

20 - 40 years of age All Phase N/A
R Robin Khapung, MD

Effect of Altitude on Postdural Puncture Headache After Caesarean Delivery

The aim of this study is to examine the effects of altitude (high altitude versus low altitude) on incidence and severity of postural puncture headache (PDPH) following spinal anaesthesia for caesarean delivery. The investigators hypothesized that the risk of PDPH would be higher in highlander parturients than in lowlander parturients.

18 years of age Female Phase N/A
G Ghulam Fatima, PhD*

Ischemic Compression Technique Versus Jones Technique in Cervicogenic Headache Patients

The primary objective of the study is to determine the effects of Jones and Ischemic compression technique on pain, range of motion and disability in patients with cervicogenic headache. Cervicogenic headache is a distinctive type of secondary headache where the pain originates from structures in the neck or cervical spine …

25 - 35 years of age All Phase N/A
M Muhammad Affan A Iqbal, MS-OMPT*

Suboccipital Muscle Inhibition Technique vs Rocabado Exercises on Cervicogenic Headache

The purpose of the study is to explore the effectiveness of Suboccipital muscle inhibition technique vs Rocabado exercises on cervicogenic headache. A randomized control trial was conducted at National Institute of Rehabilitation Medicine, Alees Medical Centre Islamabad. The sample size was 40 calculated through G-power 3.1. The participants were divided …

20 - 50 years of age All Phase N/A

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