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Found 2,203 clinical trials
A Astrid Leusink

MIBREAST Making in Immediate Breast REconstruction And the Measurement of the EffectS of RadioTherapy

Patients who require a removal of a breast (mastectomy) for breast cancer or future risk reduction often have immediate breast reconstruction (IBR). This can be performed using either an implant or the patient's own body fat to recreate the breast shape. Patients can find it difficult to imagine their own …

18 years of age Female Phase N/A
L Luca Moscetti

Real wOrld studY in the Adjuvant Setting for High Risk earLy Breast Cancer Patients

The primary goal of this observational study is to describe the distribution of treatment options and patients' characteristics according to the definition of high-risk status in the early breast cancer (EBC) setting. Participants already taking intervention as part of their regular medical care for EBC will answer questionnaires to also …

18 years of age All Phase N/A

REBECCA Real-world Early BrEast CanCer mAnagement

This is a French observational, national, multicenter prospective cohort study of patients with HER2-negative eBC treated with olaparib at their physician's discretion.

18 years of age All Phase N/A

JSKN003 Versus Treatment Of Physician'S Choice For HER2-low, Unresectable and/or Metastatic Breast Cancer Subjects

This study is a randomized controlled, open-label, multicenter phase III clinical study evaluating the efficacy and safety of chemotherapy selected by investigator JSKN003 s in subjects with recurrent or metastatic breast cancer who have previously failed first- or second-line chemotherapy in subjects with recurrent or metastatic breast cancer who have …

18 years of age All Phase 3
G Gabriella Pravettoni

Increasing Oral Medication Adherence for Metastatic Breast Cancer Patients

Aim of this study is to optimize an adherence increasing intervention designed for metastatic Breast Cancer (BC) patients by applying a full factorial design in order to evaluate the optimal combination of three different intervention components.

18 years of age All Phase N/A
S Sara Coluccelli, PhD

Implementation of Solid Digital PCR to Support Gold-standard Methods for Evaluation of HER2 Amplification Status: Focus on HER2-low Subtype

The goal of the retrospective phase of this study is to validate the specificity and the sensitivity of two Real-Time quantitative PCR based techniques in order to support the gold-standard approaches used to evaluate the HER2 gene status in breast cancer. Furthemore, HER2-low patients are enrolled in a prospective phase, …

18 years of age Female Phase N/A
A Alyson Moadel, PhD

Reiki Breast Surgery QOL Project for Women Undergoing Breast Surgery

This pilot study will examine the impact of pre-operative Medical Reiki© on the psychosocial well-being and recovery of underserved women undergoing breast cancer surgery.

18 - 99 years of age Female Phase N/A
S Sadia Saleem

Multi-center MRD Registry for Inflammatory Breast Cancer

To collect data from participants with IBC who may have had MRD testing and may have surgery in the future.

18 years of age All Phase N/A

Dose Escalated Concomitant Boost Radiotherapy for Early Breast Cancer

The goal of this prospective, single-arm, phase II, non-randomized trial is to evaluate an hypofractionation schedule with high dose simultaneous integrated tumor bed boost in early breast cancer patients. The main question\[s\] it aims to answer are: evaluate the rate of all grades of radiation-induced fibrosis at 4 years. evaluate …

18 - 50 years of age Female Phase N/A
M Mengmeng Zhang

Impact of Recombinant Humanized Type III Collagen on the Immediate and Long-term Effects of Breast Tumor Surgery

Breast tumors, particularly breast cancer, are increasingly prevalent in China, with a noticeable trend towards younger ages. Preliminary research indicates that Type III Collagen (COL3) plays a crucial role in tissue and organ protection within the tumor microenvironment and can inhibit tumor progression through microenvironmental remodeling. However, there are no …

18 - 80 years of age Female Phase 1

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