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Found 65,447 clinical trials

Utidelone Capsule Combined With Fluoropyrimidine- and Platinum-containing Therapy in First-line Treatment of Patients With Gastric or Gastroesophageal Junction Adenocarcinoma

This is a multi-national, open-label, randomized, seamless phase II/III clinical study of UTD2 combined with fluoropyrimidine- and platinum-containing therapy to evaluate the efficacy and safety in patients with locally advanced or metastatic gastric or gastroesophageal junction adenocarcinoma untreated with systemic treatment in advanced setting.

18 years of age All Phase 2/3

The Danish Bladder Cancer Group 23 Study - A European Study on Cancer in the Upper Urinary Tract

This is a study looking at how patients with a rare type of cancer in the pelvis and ureter of the kidney - called upper urinary tract urothelial carcinoma (UTUC) - is currently treated. The gold standard treatment of UTUC is the complete removal of the kidney, renal pelvis and …

18 years of age All Phase N/A
Z Zhen Song, MD

Cohort of Nursing Homes

The goal of this observational study was to establish cohorts of elderly people in hospital care and elderly people in home care.

60 years of age All Phase N/A
I Ira Goodman

A Study Evaluating the Impact of P-tau217 Blood Biomarker Testing on Early Evaluation and Management of Patients Presenting With Cognitive Complaint

The purpose of the study is to measure the difference in the proportion of participants with prespecified patient management actions between a tested interventional group and a control group.

50 years of age All Phase N/A

A Study of Amivantamab and Olomorasib Combination Therapy in Participants With Metastatic Non-Small Cell Lung Cancer

The main purpose of this study is to find out the most suitable dose (recommended phase 2 combination dose \[RP2CD\]) of amivantamab and olomorasib combination therapy and to assess how well the combination slows down or prevents the growth of tumors in participants with KRAS G12C mutant metastatic non-small cell …

18 years of age All Phase 1/2
J Juliana Schroeder, PhD

Study of Student Flourishing

The goal of this study is to learn how a science-based mobile app, called Flourish, affects student well-being. The main questions it aims to answer are: Does receiving access to the Flourish app increase well-being (e.g., positive affect, loneliness, belonging) among students? Does using the Flourish app in combination with …

18 years of age All Phase N/A
H Hongguo Dai

Phase III Clinical Trial of SHPL-49 Injection in the Treatment of Acute Ischemic Stroke

This study is designed to determine the efficacy and safety of SHPL-49 intravenous infusion in acute ischemic stroke patients.

18 - 80 years of age All Phase 3
T Tigist Belaye, MPA

Trial of Social Work Services in Fracture Clinic Setting

Every year, many Canadians sustain a fracture that requires surgical treatment and results in a long recovery period. During this recovery period, patients may experience new or worsening mental health issues including depression, anxiety, or post-traumatic stress disorder. Additionally, patients may experience new or worsening social and financial problems, such …

18 years of age All Phase N/A
V Vicenza Calvaruso

A Two-part Study to Investigate the Effects in Adults of Two Doses of Golexanolone in Patients With Primary Biliary Cholangitis (PBC) With Fatigue and Cognitive Dysfunction

The present phase 1b/2 randomised, double-blind, placebo-controlled, two-part study is designed to evaluate the safety, tolerability, pharmacokinetic characteristics and preliminary efficacy of two dose levels of golexanolone compared with placebo among subjects with a history of non-cirrhotic or Child-Pugh class A cirrhotic Primary Biliary Cholangitis (PBC) with clinically significant fatigue …

18 years of age All Phase 1/2
P Patrick Petignat, MD

Breast Cancer-Related Approach for Increasing Cervical Cancer Screening

The primary objective of this clinical trial is to assess cervical cancer screening participation among under-screened women invited through organized breast cancer screening programs in Switzerland. This randomized trial will compare three arms: Intervention group 1: Sensitization to Cervical Cancer (CC) screening Women will receive an awareness letter explaining the …

50 - 74 years of age Female Phase N/A

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