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Found 1,144 clinical trials

RCT: the Effectiveness of LifeHack in Improving Mental Wellbeing in University Students.

Psychological issues are common among university students and affect mental wellbeing. The Caring Universities (CU) project, involving nine Dutch universities, aims to enhance students' mental health through an annual online questionnaire and a platform offering guided eHealth interventions. One intervention, LifeHack, utilizes cognitive behavioral therapy-based modules to improve mental wellbeing …

16 - 99 years of age All Phase N/A

Distribution of Mood and Personality Characteristics and Their Influence on Treatment Compliance

This study intends to investigate the personality and psychological characteristics of OSA patients using classical standard scales and obtain treatment information and adherence data through prospective follow-up to summarize the distribution characteristics of mood and personality characteristics of OSA patients and their influence on treatment adherence. A thorough understanding of …

18 - 70 years of age All Phase N/A
S Sara Myers, MD

Therapy Dog Visits for Patients Hospitalized With Traumatic Injuries

Animal assisted therapy (AAT) with dogs has been shown to be beneficial for a wide range of patients with both acute and chronic illnesses, including spinal cord injuries, heart failure, myocardial infarctions, strokes, cancer, post-traumatic stress disorder, and depression. Studies have also demonstrated that even in healthy adults, the presence …

18 years of age All Phase N/A
X Xinghua Liu, PHD

Mindfulness for Emotional Distress: Neural Mechanisms

This is a randomized controlled trial examining the efficacy and neural mechanisms of a standardized Mindfulness Intervention for Emotional Distress (MIED) in adults with subclinical emotional distress. One hundred and sixty participants will be randomly assigned to either an 8-week MIED program or an 8-week Progressive Muscle Relaxation (PMR) active …

18 - 50 years of age All Phase N/A
K Krystal L Parker, Ph.D

Cerebellar Stimulation and Cognitive Control

The purpose of this study is to examine whether cerebellar stimulation can be used to improve cognitive deficits and mood in patients with schizophrenia, autism, bipolar disorder, Parkinson's disease, and major depression.

18 - 90 years of age All Phase N/A
L Lucy Beishon, MBChB

Vascular mEchanisms in, Stroke, dePression, dementiA, and deliRum: The VESPAR Project

The goal of this observational study is to determine the feasibility of using integrated Transcranial Doppler Ultrasonography or Near Infrared Spectroscopy to detect changes in cerebral autoregulation and neurovascular coupling in healthy, stroke, dementia, depression and delirium populations. We also aim to: Determine the optimal stimulus for neurovascular coupling To …

65 years of age All Phase N/A
M Moran Amit, MD

TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors

This clinical research study is to learn about the feasibility, safety, and effects of psilocybin-assisted psychotherapy for cancer survivors with depression and/or anxiety.

18 years of age All Phase 2
E Elizabeth Loynd

Adapting and Pilot Testing a Skills-based Smoking Cessation Intervention to Address Developmental and Health-related Stress Among Adults Who Smoke

Smoking remains the leading preventable cause of death in the United States, and there are persistent and significant disparities in tobacco use among transgender and gender diverse (TGD) individuals. Stigma, discrimination, gender dysphoria, and other gender minority stressors likely contribute to these disparities, and the increased burden of gender minority …

18 years of age All Phase N/A
L Loa Clausen, PhD

Profiling the Dynamic of Binge Eating Disorder (PRODY-BED)

The goal of this observational study is to explore if different and specific profiles can be identified in adults with binge eating disorder (BED) depending on their additional eating pathology, emotion regulation and executive functions. The main questions it aims to answer are: Is there different and specific subgroups of …

18 years of age All Phase N/A
F Federica Sancassiani, PsyD, PhD

Non-pharmacological Care for Depression in Cancer Patients Using VR and TMS

Despite its significant impact on individuals and healthcare systems, substantial gaps remain in the clinical and rehabilitative management of depression in oncology patients. Depression in cancer patients is often under-recognized and untreated, and screening tools and structured healthcare pathways are lacking. Even when depression is identified in oncology patients, evidence …

18 - 100 years of age All Phase N/A

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