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Found 171 clinical trials
C Chase Wooley, BS

Fundus Ablation Registry (Gastric Fundus Mucosal Ablation for Weight Loss)

The purpose of this study is to construct a multi-site, prospective registry to evaluate the clinical outcomes of patients who have undergone gastric fundus mucosal ablation at True You Weight Loss.

18 - 65 years of age All Phase N/A
S Sue Shapses, PhD

Metabolic Health, Bones and Nuts During Weight Loss in Adults

The aging population is rapidly increasing, and it is important to identify dietary factors that can prevent disease and promote health in this group. Legumes, such as peanuts, are a plant-based food high in protein and unsaturated fat making this a healthy choice but are not consumed frequently enough in …

50 - 75 years of age All Phase N/A
K Kuat P Oshakbayev, professor

Effectiveness of Weight Loss Methods on Lifespan for Metabolic Syndrome

Background. The prevalence of type 2 diabetes mellitus (T2D) in the world is constantly increasing. Treatment of T2D is complicated by arterial hypertension and obesity (metabolic syndrome - MS). Cardiovascular complications are the main cause of death in patients with MS. Objective weight loss improves clinical and laboratory parameters in …

35 - 65 years of age All Phase 4
K Kalpna K Durairaj, MD

Restoring Facial Volume After GLP-1 Weight Loss With Radiesse

The goal of this clinical trial is to evaluate the potential of Calcium Hydroxylapatite (CaHA) to restore facial volume and improve skin quality in patients with GLP-1 receptor agonist-associated facial volume loss. Participants will: Schedule first dose of a prescribed GLP-1 receptor agonist drug to coincide with the baseline visit …

21 - 65 years of age All Phase 4
M Maria L Balmer, Prof. med.

The FaibaGo Study - Long-Term Weight Reduction Via Low-Threshold Intervention

The main aim of this study is to assess the effect of a chewing gum containing galactooligosaccharides (GOS) on the body mass index (BMI), the metabolism and the oral and intestinal microbiomes in a population of overweight adults.

25 years of age All Phase N/A
M Mary Webb

ADAPT Study: Assessing Diet, Appetite and Physiology Throughout Weight Loss Study)

Behavioral weight loss programs for obesity can result in weight loss and health benefits. However, behavioral weight loss often stops despite efforts to continue losing weight, this can be called an involuntarily weight loss plateau. This study investigates changes in metabolism and/or the brain that contribute to the occurrence of …

18 - 60 years of age All Phase N/A

Optimizing Telehealth-delivery of a Weight Loss Intervention in Older Adults

This study seeks to answer the fundamental questions of which initial, first-line weight loss intervention should be offered to older adults with obesity and multiple chronic conditions and how to address the high non-response rates observed with most conventional strategies. A sequential, multiple assignment, randomized trial (SMART) design will permit …

65 - 85 years of age All Phase N/A

FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)

The goal of this clinical trial is to learn the best combination of family components that yields optimal weight loss among Black adults. The main question it aims to answer is: What combination of four family components in combination with a standard behavioral weight loss program yields optimal weight loss …

18 - 75 years of age All Phase N/A
K Karen E Hatley, MPH, RD

Piloting a Generative Artificial Intelligence Chatbot in a Mobile Weight Loss Program

The goal of this study is to learn if integrating a chatbot into an existing 12-week smartphone-delivered behavioral weight loss program is feasible and effective for weight loss among young adults. Researchers will compare a standard behavioral weight loss program for young adults that delivers 1-2 brief messages per day …

18 - 39 years of age All Phase N/A
H Haris Rathore

Low-Dose Semaglutide for Weight Loss in Obese Non-Diabetic Pakistani Adults

This prospective, open-label, single-arm, single-center interventional pilot trial aims to evaluate the efficacy and safety of low-dose semaglutide for weight loss and cardiometabolic improvement in obese Pakistani adults without type 2 diabetes mellitus. The study will be conducted at the Asian Institute of Medical Sciences (AIMS), Hyderabad, Sindh, Pakistan. A …

18 years of age All Phase 4

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