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Found 288 clinical trials
T Tehreem H Doctor, MBBS

Comparison of Post-operative Outcomes Between ERAS Protocol and Non-ERAS Local Regimen in Patients Undergoing Thyroidectomy

Patients undergoing thyroidectomy in hospital setup will be compared by applying ERAS protocol to one group and non ERAS local regimen to other group. Then comparison will be made in terms of length of hospital stay in days and time for ambulation in hours. Results will be compared showing which …

18 - 60 years of age All Phase N/A
R Renate Kollevåg Vik, PhD

Patient-centered Dosage of Levothyroxine

Levothyroxine is the most used thyroid hormone replacement when the thyroid gland is failing. Because dosage adjustment normally takes several months, the investigators have developed a decision support tool (DST) that predicts optimal dosage based on repeated blood samples the first 2 weeks after initiation of therapy. In this randomized …

18 years of age All Phase N/A
J Jianyong Lei, MD

A Study of Online Follow-up in Patients With Papillary Thyroid Cancer

The randomized, actively controlled, non-inferiority trial is scheduled to begin in August 2024 and run through August 2026. Inclusion criteria: (1) has undergone microwave ablation of thyroid or thyroidectomy (including endoscopy and opening) at the Department of Thyroid Surgery of West China Hospital of Sichuan University, (2) is between 18 …

18 - 90 years of age All Phase N/A

A Study to Collect Information About the Use of Redifferentiating Medications as a Standard Treatment for Thyroid Cancer

The purpose of this study to learn more about the use of redifferentiating medications as a standard treatment for radioactive iodine/RAI-refractory thyroid cancer. This study is a registry study.

18 years of age All Phase N/A
L Ling Zhan, Doctor

Renovated Prediction Model for Difficult Transoral and Submental Endoscopic Thyroidectomy

The investigators have previously proposed a prediction model for difficult transoral and submental thyroidectomy through a retrospective study. In order to better promote transoral and submental endoscopic approach for thyroid surgery and to set up an appropriate training course, the investigators aim to renovate and validate the prediction model through …

years of age All Phase N/A
P Philip Friedlander, MD PhD

Correlation Vitamin D Level to Endocrine Autoimmune Toxicity Due to Immune Checkpoint Inhibitors

The purpose of this research study is to see if the amount of vitamin D in ones blood makes it more or less likely to develop thyroid gland toxicity when being treated with immunotherapy that blocks the activity of proteins called programed death-1(PD-1) or programmed death ligand-1 (PD-L1). Immunotherapy is …

18 years of age All Phase N/A
G Gabor Szinnai, Prof. MD, PhD

Prospective Evaluation of OptiThyDose

The aim of this multicentric, randomised, two-arms and single-blinded clinical trial is to prospectively evaluate OptiThyDose for Congenital hypothyroidism (CH) and Graves' disease (GD).

- 18 years of age All Phase N/A
M Magdalena Bogdanovska Todorovska, MD, PhD

NIRAF-Guided Parathyroid Identification During Thyroidectomy

This study evaluates whether a wearable near-infrared autofluorescence (NIRAF) imaging system can help surgeons identify and preserve parathyroid glands during thyroid surgery. These small glands produce parathyroid hormone (PTH), which helps control blood calcium. The modified Meta Quest stereoscopic goggles display fluorescence naturally emitted by parathyroid tissue; no injected dye …

18 years of age All Phase N/A
L Ling Zhan, Doctor

Surgical Competency for Robot-Assisted Thyroidectomy: Construction and Validation of a Robotic Thyroidectomy Assessment Score (RTAS)

To develop and validate a structured scoring tool (robotic thyroidectomy assessment score, RTAS) for assessing and quantifying surgical performance in robotic thyroidectomy (RT).

years of age All Phase N/A
H Heijboer

Improvement of Laboratory Diagnostics in Hypothyroid Patients Using Levothyroxine

Hypothyroidism is a thyroid disorder and one of the most common endocrine disorders. Hypothyroidism can have multiple causes; most patients suffer from primary autoimmune hypothyroidism (Hashimoto's disease), but also central hypothyroidism, hypothyroidism after total thyroidectomy due to thyroid carcinoma, or hypothyroidism due to therapy of Graves' disease occur. Most patients …

18 - 100 years of age All Phase N/A

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