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Found 172 clinical trials
K Kathryn E Demos McDermott, PhD

Cognitive Strategies for Weight Loss

The goal of this clinical trial is to compare weight change and other related outcomes associated with three different behavioral weight loss interventions (STANDARD Behavioral, PREVENT, and PROMOTE) in adults with obesity. The main questions it aims to answer are: Which of the three Internet-delivered weight loss programs results in …

18 - 70 years of age All Phase N/A
F Family Medicine Research Study Coordinators

Weight Loss Through Mayo Clinic Diet

The purpose of study is to evaluate the efficacy of the Mayo Clinic Diet in clinically significant weight loss (\>5%) versus usual care. We also wish to evaluate the feasibility, barriers to completion, and sustainability of this intervention at the 24, and 52-week marks. Lastly, we aim to study the …

18 - 64 years of age All Phase N/A
H Hande Gül Ulusoy Gezer, MSc

Weight Loss and CLOCK 3111T/C Polymorphism

The goal of this observational study is to investigate the relationship of CLOCK 3111T/C (rs1801260) gene variant with nutritional habits, nutritional status, chronotype, sleep quality, some biochemical parameters in overweight or obese individuals and to observe its effect on weight loss diet intervention. The main questions it aims to answer …

20 - 50 years of age All Phase N/A
S Sharon O'Toole, M.A.T.

Control Systems Engineering for Weight Loss Maintenance

This project capitalizes on principles of control systems engineering to build a dynamical model that predicts weight change during weight loss maintenance using behavioral, psychosocial, and environmental indicators evaluated in a system identification experiment. A 6-month behavioral obesity treatment will be administered to produce weight loss. Participants losing at least …

18 - 70 years of age All Phase 2
B Bin Li, MD

Thread Embedding Acupuncture Therapy for Weight Loss

Obesity is the most prevalent chronic disease worldwide, affecting approximately 800 million adults. Excess adiposity and its numerous complications, including cardiovascular disease and type 2 diabetes, impose a considerable economic burden and constitute major contributors to global morbidity and mortality. Treatments that result in substantial weight reductions may improve outcomes …

18 - 75 years of age All Phase N/A
C Camille S Worthington, PhD

Time-restricted Eating for Postpartum Weight Loss

This study is being done to assess the feasibility and acceptability of a time-restricted eating intervention among postpartum women with overweight/obesity.

18 years of age Female Phase N/A
P Principal Investigator

Weight Loss Management in Endometrial Cancer Survivors

This study is being done to understand how oncologists can engage a multidisciplinary team to help endometrial cancer survivors with obesity to engage in a weight management program and potentially start a weight loss medication. Obesity often impacts the future health and longevity of early-stage endometrial cancer survivors more than …

18 years of age Female Phase N/A
H HongQuan Xie, PhD

Time-Restricted Eating for Weight-Loss Maintenance

Weight regain after intentional short-term weight loss is a common challenge. It often undermines the long-term benefits of obesity treatment. This study is a multi-center 2-arm randomized controlled trial across six regions in China, specifically targeting overweight or obese adults who have recently achieved a short-term weight reduction (≥5% of …

18 - 65 years of age All Phase N/A
J Jenny Ho

BEAM for Weight Loss - a Pilot Study

Bariatric endoscopic antral myotomy (BEAM) is a novel endoscopic technique which is performed using a gastroscope under general anesthesia. It involves cutting the muscle fibers at the gastric antrum, thereby weakening the antral pump, delaying gastric emptying and inducing satiety. Early reports had shown that this technique can produce significant …

18 - 70 years of age All Phase N/A
M Mohamed Abeid, MD

Endo-Band: Endoscopic Band Ligation for Weight Loss

To the best of our knowledge, this is the first study to use endoscopic band ligation for weight loss. All ligatures will be performed in the gastric body starting at the distal body; 5 parallel rows, with the last one in the proximal body.The entire procedure can be completed in …

18 - 65 years of age All Phase N/A

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