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Found 63,122 clinical trials
Y Yu Han

Association of Gestational Cardiovascular Health With Pregnancy Outcomes

Pregnancy is a critical period for cardiovascular health risk assessment and interventions to reduce the incidence of cardiovascular disease in both mother and child generations. Recently, the American Heart Association proposed the latest cardiovascular health assessment indicator "Life's Essential 8". However, there is still a lack of application data for …

20 - 49 years of age Female Phase N/A

A Stepped Care Approach to Treating Dental Fear

The purpose of this study is to compare an intervention for dental fear to the usual approach (i.e., whatever participants' dentist typically does to help participants manage their fear). The dental fear intervention has 2 separate steps. Step 1 (the less intensive or 'light touch' intervention step) involves using a …

13 - 99 years of age All Phase N/A
P Pietro Panni, P.I./MD

Poor Grade Aneurysmal Subarachnoid Hemorrhage Study Group

Multicentric registry study in order to define outcome, predictors, treatment effects and their modifiers in poor grade aneurysmal subarachnoid haemorrhage patients. The search for outcome predictors is going to be subdivided into three main research areas: outcome predictors in the emergency department (so called "early brain injury phase"). outcome predictors …

18 years of age All Phase N/A
D Daniel Kim, MD

Trifecta-Heart cfDNA-MMDx Study

Demonstrate the relationship between DD-cfDNA levels and HLA antibodies in blood transplant recipient and the Molecular Microscope® (MMDx) Diagnostic System results in indication and protocol biopsies from heart transplants.

years of age All Phase N/A
T Tarun Chakravarty, MD

Assessment of TRanscathetEr and Surgical Aortic BiOprosthetic Valve Thrombosis and Its TrEatment With Anticoagulation

This is a prospective study designed to evaluate the structural and functional integrity of transcatheter or surgical bioprosthetic valves with multimodality imaging. The study further aims to confirm resolution of the early bioprosthetic valve thrombotic changes with anticoagulation.

18 years of age All Phase N/A
y yolande COSTA

Postoperative Morbidity and Mortality After Cardiac Surgery

The local database results from a joint initiative of anesthesic, cardiology and cardiac surgery departements.Its purpose is to record in an exhaustive fashion all the interventions of cardiac surgery performed under extracorporeal circulation in adults at Bichat hospital.This database includes the preoperative characteristics of the patients, the type of surgery, …

18 years of age All Phase N/A
G Gadisa D Ejeta

Reducing Mortality in Adults With Advanced HIV Disease (REVIVE)

A double blinded, placebo-controlled, multicenter trial to evaluate effectiveness of azithromycin prophylaxis on mortality in advanced HIV.

18 years of age All Phase 3
A Amelia Rudd, HND

Is There a Genetic Predisposition for Acute Stress-induced (Takotsubo) Cardiomyopathy

Acute stress-induced (takotsubo) cardiomyopathy or broken heart syndrome presents like a heart attack, classically is triggered by intense emotional or physical stress and can have serious health consequences. In the current study the investigators wish to establish whether there is a genetic predisposition making certain people more susceptible to this …

years of age All Phase N/A
V Victor DE LEDINGHEN

Prognosis Value of Non-invasive Methods for the Diagnosis of Chronic Liver Disease

The aim of this retrospective and prospective study is to evaluate the 20-year prognosis value of non-invasive methods for the diagnosis of chronic liver disease for predicting survival and complications of cirrhosis.

18 years of age All Phase N/A
N NIEHS Join A Study Recruitment Group

Immune Cell Response to Stimuli

This study will investigate the response of immune cells (neutrophils, monocytes) to various signals in the test tube to determine how they sense the signals in the body and what substances they produce in response to them. It will determine how the cells may, under certain circumstances, contribute to inflammation, …

18 - 65 years of age All Phase N/A

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