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Community-Based Lifestyle Intervention for Diabetes Prevention in Arab Women

Arab women present increased risk for diabetes, with a 70% greater risk for adult-onset diabetes and a significantly younger age at onset compared with Jewish Israelis. In fact, the rate of diabetes for Arab women in Jerusalem is 4 times higher compared with their Jewish counterparts. Group lifestyle interventions such …

18 years of age Female Phase N/A
A Antonio Cano Sánchez, MD

Promotion of Healthy Eating Behaviors in Type 2 Diabetes Patients

Intervention designed to promote healthy eating in patients with type 2 diabetes.

50 - 75 years of age All Phase N/A
V Violeta Raverdy, MD

Comparison of Gastric By-Pass and Optimized Medical Treatment in Obese Diabetic Patients

The objectives are to compare the results of the Gastric By-Pass (GBP) to that of optimized medical therapy in patients with obesity and poorly controlled type 2 diabetes in terms of mortality, weight loss, glycemic control, quality of life, cost, cost-effectiveness and cost utility of these two strategies.

18 - 65 years of age All Phase 4

Addressing Diabetes by Elevating Access to Nutrition

The goal of ADELANTE is to determine whether a multi-level intervention to improve household food insecurity and glycemic control is effective for Latino patients with diabetes. Specifically, ADELANTE aims to determine whether weekly household food delivery plus an intensive lifestyle intervention is more effective than usual care for improving glycemic …

18 years of age All Phase N/A
S Sheng-Lun Kao, MD

Effectiveness of Integrated Care Combined Nutrition and Lifestyle Counselling in Frail Older Patients With Diabetes

The goal of this clinical trial is to evaluate the effectiveness of innovative integrated care in pre-frail or frail patients with diabetes over 65 years old. The main questions it aims to answer are: To establish innovative integrated care for frail elderly patients with diabetes combined with nutrition and lifestyle …

65 years of age All Phase N/A
K Keyanni Johnson

WISE-2B Brain Study (Weight Loss Intervention Surgical Effects on Brain Function)

The goal of the study to understand the effects of weight loss and improvements in diabetes following bariatric surgery on brain function and thinking. This study will also examine whether non-invasive transcutaneous vagal nerve stimulation (tVNS) intervention initiated 30 days post-surgery improves brain function and thinking. The study does NOT …

20 - 75 years of age All Phase N/A
L Lijuan Sun, PhD

Brown Fat as Therapeutic Strategy for Obesity and Associated Metabolic Diseases Via Functional Food/Nutraceutical Approach - Molecular Mechanisms of Pentacyclic Triterpenes (BRACE)

To examine MA (Maslinic Acid) safety and efficacy in ameliorating insulin resistance and the cardinal features of metabolic syndrome. Chronic exposure to MA as a potent PPARgamma binder nutraceutical over 12 weeks will result in improvement in the features of metabolic syndrome including waist circumference, blood pressure, serum HDL-C level, …

21 - 60 years of age All Phase N/A
A Ana Carolina F Bonafe, MS

Comparison of Palatal Wound Healing in Diabetic and Non-diabetic Patients

This study aims to characterize and compare the closure of open wounds in the palatal mucosa of diabetic and non-diabetic patients, evaluate clinical, patient-centered and immunological parameters as well as wound microbiome composition.

18 - 80 years of age All Phase N/A
F Fernando Gerchman, PhD

Effect of Partial Dietary Replacement From Animal to Plant-Based Protein for Type 2 Diabetes Management

The goal of this clinical trial is to examine the effect plant-based diet, with a partial replacement of animal protein by plant protein, in blood sugar levels and other health risks of people with type 2 diabetes and excessive weight. The plant-based diet will be compared to a standard healthy …

18 - 65 years of age All Phase N/A
J Jeanette Laugen

Glucagon Suppression by Hyperglycemia in the Presence and Absence of Amino Acid Infusion

This study is being done to better understand how amino acids alter the release of glucagon and insulin compared to glucose alone in health and disease.

25 - 65 years of age All Phase 4

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