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Found 570 clinical trials
M Megan Swiger

Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer

The overarching objective of this project is to develop a pan-gynecologic cancer detection test using gynecologic (unique endometrial, cervical, and ovarian cancer) cancer-specific methylated DNA markers and high-risk human papilloma virus (HR-HPV) detected in vaginal fluid and/or plasma. This proposal defines Phase II MDM-based cancer detection studies in endometrial cancer …

18 years of age Female Phase N/A
T Taejong Song, MD PhD

KOrean Borderline Ovarian Tumor (KOBOT) Registry

The aim of this study is to collect data on Korean patients with borderline ovarian tumors.

years of age Female Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

Background Some genes may be associated with a greater chance of side effects during cancer treatment. These genes may also make certain treatments less effective. Researchers want to collect blood or cheek swab samples from people having cancer treatment to study these genes. Objectives To obtain a blood or cheek …

3 years of age All Phase N/A
A Anna Giudici, MD

Retrospective Evaluation of Minimally-Invasive Surgical Strategies in Ovarian Neoplasms (REMISSION Study)

This observational study aims to evaluate the outcomes of patients with early-stage epithelial ovarian cancer who are treated with minimally invasive surgery (such as laparoscopic or robotic surgery). Specifically, the study will look at: Post-Surgery Complications What is the rate of complications within 30 days after surgery? How often do …

years of age Female Phase N/A
D Dr. Lucy Gilbert, MD,MSc,FRCOG

DOvEEgene: Diagnosing Ovarian and Endometrial Cancer Early Using Genomics

This study aims to develop and validate a test for diagnosing ovarian and endometrial cancers early. It relies on detecting somatic mutations that are associated with these cancers in a biofluids sample taken from the cervix and the uterine cavity.

18 years of age Female Phase N/A
D Dominique GENRE, MD

Institut Paoli Calmettes Ovarian Cancer Database

Database of Institut Paoli-Calmettes patients diagnosed with ovarian cancer

18 - 95 years of age Female Phase N/A
D Dr. Lucy Gilbert, MD,MSc,FRCOG

DOvEE - Diagnosing Ovarian & Endometrial Cancer Early

This study hopes to improve early detection of ovarian and endometrial cancers. It will determine if women with bloating, abdominal distension, abdominal/pelvic pain, increased urinary frequency and/or early satiety, benefit from earlier surgery after screening by CA-125 ovarian cancer biomarker and transvaginal ultrasound.

45 years of age Female Phase N/A
Y Yuan Li, Doctor

A Cohort Study of Hereditary Ovarian Cancer Risk Prediction Models and Pathogenesis Exploration

The aim of this project is to establish a bidirectional multicenter cohort of hereditary ovarian cancer and to describe the clinicopathologic features of hereditary ovarian cancer patients in our country. The risk prediction model of ovarian cancer for Chinese was established by following-up analysis of clinical and pathological information, genetic …

18 years of age Female Phase N/A
S Samuel Wolf, DO

A Diagnostic Test to Evaluate Cancer Risk Before Surgery in Women with an Ovarian Mass

Ovarian cancer is a serious health risk with the highest death rate among gynecological cancers. Unfortunately, it's only possible to definitively diagnose ovarian cancer after surgery, as there are no reliable tests to determine if an ovarian abnormality is cancerous or benign before surgery. Cleo Diagnostics have developed a new …

18 years of age Female Phase N/A
F Federico Ferrari, MD, PhD

Adherence and Compliance to ERAS in Gynecological Surgery

The aim of the study is to investigate the association between early non-compliance to ERAS in postoperative day 2 (POD2) with the rate of postoperative complications.

18 - 75 years of age Female Phase N/A

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