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Found 65,259 clinical trials

Long-Term Follow-up Study of Early Stage Breast Cancer Patients Included in GEICAM Studies

This is a multicenter, cohorts study to collect information from patients diagnosed with early-stage invasive breast cancer who have been previously included in a neoadjuvant or adjuvant clinical trial of the GEICAM group. Patients will be included in this study from the moment of completion of the follow-up of the …

18 years of age Female Phase N/A
R Rui Huang, M.D., Ph.D.

"Real-life" Cohort Study on Patients With Chronic HBV Infection in Jiangsu

Hepatitis B virus (HBV) infection remains one of the most serious health problems worldwide. Patients with chronic HBV infection are at an increased risk for developing hepatic cirrhosis, hepatocellular carcinoma and even death. Although some predictive factors of the outcome of chronic HBV infection were identified, more precisely determine the …

years of age All Phase N/A
J Jannet Beukema

Standard Follow-up Program Cervix Cancer (SFP CERVIX)

The goal of this clinical trial is to learn the safety, tolerability and pharmacokinetics of single and multiple doses of HY8931 in healthy adult participants. The main questions it aims to answer are: How is the safety and tolerability following administration of single and multiple doses of HY8931 in healthy …

years of age Female Phase N/A
S Sophie Bayle-Bleuez, MD

LIquid BIopsies in Patients Presenting Non-small Cell Lung Cancer

The goal of this project is to characterize the genetic profile of patients with advanced stage IIIB/IV non-small cell lung cancer (NSCLC) using liquid biopsies

18 years of age All Phase N/A
S Sylvie Bonvalot, MD

REtroperitoneal SArcoma Registry: an International Prospective Initiative

Surgery is currently the only potentially curative treatment modality for localized retroperitoneal sarcoma (RPS). Available studies regarding oncologic outcomes are mainly retrospective in nature, and RPS are recognized as a rare disease. Therefore, prospective analysis of high quality data is a top priority. Primary Objectives of this study are: to …

18 years of age All Phase N/A
A Aurélien SCALABRE

Prognosis Factors for the Treatment of Pectus Carinatum With a Dynamic Compression System

Pectus carinatum is a deformation of the thoracic wall causing an aesthetic prejudice. Since 2011, our team uses a dynamic compression system to treat this deformation. It is a harness that the patient wears all day long for an average duration of 1 year, and that remodels the chest by …

6 - 40 years of age All Phase N/A
B Bryce Hockman

Molecular Mechanisms Associated With Breast Implant Complications

Bacterial biofilms cause implant failures, chronic inflammation, and immune polarization. The study investigates the possible role of bacterial biofilm as a factor in the etiology of Breast Implant Illness. Three patient cohorts will be studied (A) Subjects with breast implant with BII manifestations (B) Subjects with breast implants without BII …

18 years of age Female Phase N/A
L Lauriane EBERST, MD

Adapting Treatment to the Tumor Molecular Alterations for Patients With Advanced Solid Tumors: MyOwnSpecificTreatment

The MOST Plus study is a two-period phase II clinical trial, conducted in patients with all types of progressive solid tumors after at least 1 prior systemic treatment regimen for advanced disease (in the absence of a validated second line therapy). The main goal of this study is to evaluate …

18 years of age All Phase 2
J Jeffrey D Horbar, MD

Vermont Oxford Network Very Low Birth Weight Database

Vermont Oxford Network maintains a database for live born infants \<=1500 grams or \<=29 weeks gestational age who are born at participating hospitals or admitted to them within 28 days of birth, regardless of where in the hospital the infant receives care.

- 28 years of age All Phase N/A

A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular Lymphoma

This study is researching an experimental drug called odronextamab, referred to as study drug. The study is focused on participants with previously untreated follicular lymphoma (a type of non-Hodgkin lymphoma or NHL). This study will be made up of two parts: Part 1 (non-randomized) and Part 2 (randomized - controlled). …

18 years of age All Phase 3

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