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Found 890 clinical trials
E Eline Panadevo, MD

Optimised Cardiovascular and Renal Protection in Patients With Chronic Kidney Disease and Cardiovascular Disease

The goal of this clinical trial is to investigate whether care in a specialised Cardio-Renal Clinic can improve the health of people living with both cardiovascular disease and chronic kidney disease. The clinic brings together expertise in heart and kidney disease and provides structured treatment based on current clinical guidelines. …

18 years of age All Phase N/A
N Nehal Vekariya, MS

CARBON: UAB Cardiovascular Research Biobank

The UAB Cardiovascular Research Biobank (CARBON) will be a resource that contains biological materials, such as DNA samples, in addition to health and personal information on a large number of people over time. It will be set up so that it can be used in the future as a resource …

18 years of age All Phase N/A
S Saurabh S Thosar, PhD

Sleep Duration and Cardiovascular Health

This is a cross-sectional study with an optional intervention that will examine how extreme sleep durations relate to cardiovascular health, physical activity, and sleep quality by studying three groups of participants: short sleepers (≤ 6 hrs), long sleepers (≥ 9 hrs), and average duration sleepers (7-8 hrs). The optional intervention …

25 - 65 years of age All Phase N/A
T Tammy Yeung

Cardiovascular Physiological Signal Recording Project

Vital sign monitoring is important for patients, especially those with underlying cardiovascular diseases. Traditional monitoring including SaO2, blood pressure, pulse, rhythm monitoring can be cumbersome, with wires and cuff attached to a patient. This can lead to reduced compliance, especially in uncooperative patients or young kids. The use of photoplethysmography …

18 years of age All Phase N/A
M Mahmoud M Loubani, MD

Nutritional Screening in Cardiovascular Disease

This is a nutritional screening and assessment study conducted prior to heart surgery. The nutritional status of patients will be assessed by a series of questionnaires, blood/urine biomarkers and measurement of grip strength and body composition. The investigators will then evaluate of any of the assessments are linked with clinical …

40 - 85 years of age All Phase N/A
K Ke-Yun Chao, M.Sc

Nutritional Effects in Cardiovascular Surgery

This study aims to investigate the distribution of gut microbiota-derived metabolites, and to evaluate whether postoperative nutritional intervention can modulate the gut-heart metabolic axis, thereby improving metabolic profiles and clinical outcomes.

50 - 80 years of age All Phase N/A

The Cardiovascular Impact of Hot Flushes

The overall objective of this study is to examine the physiological responses that occur during a hot flush in postmenopausal women. The following specific aims will be executed to reach the overall objective of this study. Aim 1: To determine if hot flushes can be reliably induced with a temperature-controlled, …

40 - 70 years of age Female Phase N/A
A Angela Koh, M.D.

Exercise to Slow Cardiovascular Ageing Progression

In ageing, deleterious alterations in cardiovascular (CV) structure and function increase risks of ageing-related cardiovascular disease (CVD). Investigators found that these CV alterations were associated with circulating serum metabolites, suggesting a metabolic basis to CV ageing. Investigators hypothesize that modification of these metabolites by intervention, such as exercise, may retard …

21 - 100 years of age All Phase N/A
M Mehrdad Arjomandi, MD

Secondhand Tobacco Smoke and Cardiovascular Disease

This is a double-blind randomized placebo-controlled crossover clinical trial of efficacy and safety of an FDA-approved angiotensin receptor blocker (losartan) to improve cardiopulmonary outcomes in individuals with pre-Chronic Obstructive Pulmonary Disease (COPD) due to prolonged exposure to secondhand tobacco smoke.

40 years of age All Phase 4
J Jade Hayden

IPSC Repository of Pediatric Cardiovascular Disease

Obtain blood samples for generation and maintenance of induced pluripotent stem cells (iPSCs) and genomic/DNA sequencing for biomedical research that will improve the understanding and treatment of pediatric cardiovascular disease

years of age All Phase N/A

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