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Found 1,604 clinical trials

A Trial Comparing Efficacy, Tolerability, and Safety of GZR101 Injection Once Daily (OD) and GZR33-70 Injection OD

This trial is conducted in China. The aim of the trial is to compare the efficacy, tolerability, and safety of GZR101 Injection and GZR33-70 Injection in type 2 diabetes inadequately controlled on basal/ premixed insulin once daily at least with or without pre-dinner meal-time insulin.

18 - 75 years of age All Phase 2
X Xiaolan Yong, bachelor

A Study of HRS9531 in Participants With Impaired Kidney Function and Healthy Subjects

The purpose of this study is to assess how fast HRS9531 gets into the blood stream and how long it takes the body to remove it in participants with impaired kidney function compared to healthy participants.

18 - 65 years of age All Phase 1
D Dike Ojji, MBBS, PhD

Diabetes Management for Primary Healthcare Centers.

The purpose of this study, "Integrating diabetes care into Primary Healthcare Centers (PHCs) in Abuja, Nigeria: a pilot study," is to screen, diagnose, treat, and educate diabetes patients in two selected PHCs in Abuja. This single-arm pilot trial will test the feasibility of integrated diabetes care, measure the implementation outcomes, …

18 - 99 years of age All Phase N/A

Implementation of Team Clinic for Type 2 Diabetes (TCT2)

The goal of this clinical trial is to learn if shared medical appointment is an acceptable way to deliver care to youth with type 2 diabetes. The main question[s] it aims to answer are: Is shared medical appointments an acceptable care delivery model for this population? Does shared medical appointment …

12 - 18 years of age All Phase N/A
J Jun Hwee Benjamin Lee

The PACT (Patient Activation Through Conversations) Study

The PACT Study is a cluster randomised trial of a health coach-led patient activation program in type 2 diabetes. The goal of this clinical trial is to evaluate the effectiveness of a health coaching intervention (PACT program) led by Care Coaches (trained lay persons), in adult participants with sub-optimally controlled …

21 - 64 years of age All Phase N/A
Z Zhimin Huang, MD. & PhD.

Validation of Insulin Dose Prediction Model Based on Artificial Intelligence Algorithm

The present study aims to conduct a prospective controlled trial comparing an LSTM-based artificial intelligence (AI) prediction model and clinicians' experience in the efficacy and safety of blood glucose control in hospitalized patients with type 2 diabetes mellitus (T2DM) receiving continuous subcutaneous insulin infusion (CSII) treatment in the Department of …

18 - 75 years of age All Phase N/A
B Beryl O'Donnell, MSN, RN, NP-C

Culturally Tailored Diabetes Education on Self-Management of Adult Hispanic Males With Type 2 Diabetes Mellitus

Diabetes mellitus (DM) is a global public health concern. In the United States, adult Hispanic males are particularly vulnerable to type 2 diabetes mellitus and are more likely to develop complications and subsequently die from it, compared to non-Hispanic White males. Evidence suggests good self-management behaviors can potentially prevent disease-related …

18 - 64 years of age Male Phase N/A
R Ralph DeFronzo, MD

Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants

Our goal of the study is to learn the effects of the diabetes medication named Pioglitazone, in type-2 diabetic obese participants with Heart failure. The main question it aims to answer are To demonstrate that impaired mitochondrial function leading to reduced ATP generation plays a key pathophysiologic role in the …

30 - 70 years of age All Phase 4
S Similan Kirisri

Cognitive Behavioral Therapy for Insomnia in Type 2 Diabetes Mellitus

This study will explore the effects of cognitive behavioral therapy for insomnia (CBTI) compare to health educations in patients with type 2 diabetes (T2DM) with insomnia symptoms.

30 - 65 years of age All Phase N/A

Postprandial Profiles of Metabolites and Appetite-regulating Hormones in Plasma and Cerebrospinal Fluid

Overweight and obesity are rising in prevalence and becoming a growing threat to public health. Obesity is associated with an increased all-cause mortality, impaired quality of life, and numerous of disorders. Therapeutic strategies against obesity - which include an abundance of dietary and physical training programmes and pharmaceutical drugs to …

50 - 70 years of age Male Phase N/A

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