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Found 890 clinical trials
D Duck-chul Lee, PhD

Dose-Response to Resistance Exercise on Cardiovascular Health

A large body of evidence indicates numerous health benefits of physical activity, including prevention of cardiovascular disease (CVD), the leading cause of death in the US. This evidence has led to US Physical Activity Guidelines that recommend ≥150 min/week of moderate or ≥75 min/week of vigorous aerobic exercise (AE), plus …

40 years of age All Phase N/A
H Haidong Kan, PhD

Acute Effects of Cold Exposure on Cardiovascular System

This is a randomized controlled human exposure crossover study. Investigators aim to assess the acute effects of low temperature exposure on cardiovascular system and the underlying mechanisms.

18 - 30 years of age All Phase N/A
G Gamze Koyutürk, Asst. Prof

Circadian Rhythm and Cardiovascular Recovery After Submaximal Exercise

This cross-sectional, observational, and analytical study aims to investigate the relationship between morningness-eveningness characteristics and cardiovascular recovery after a submaximal exercise test in healthy individuals aged 18-45 years. Circadian preference will be assessed using the Morningness-Eveningness Questionnaire, sleep quality will be assessed using the Pittsburgh Sleep Quality Index, and cardiovascular …

18 - 45 years of age All Phase N/A

Breast Artery Calcification (BAC) and Female Cardiovascular Disease

The investigators are recruiting women with and without Breast Artery Calcification (BAC) on their mammograms. Each participant in the study will undergo bloodwork at a Northwell Health lab, a cardiac CT scan, and fill out some brief questionnaires. Results will be shared with the respective participant. At the conclusion of …

55 - 65 years of age Female Phase N/A
H Hua Zheng

Exploring of Serum Biomarkers of Delirium After Cardiovascular Surgery

The incidence of postoperative delirium in patients after cardiovascular surgery is very high, which seriously affects the short-term and long-term prognosis of patients, but its mechanism is not clear. Recent studies have found that lactic acid participates in the process of sepsis by inducing histone lactatation in macrophages. histone H3 …

18 years of age All Phase N/A
H Haoxin Gu

Noninvasive Real-Time Arterial Waveform Monitoring for Cardiovascular Disease Assessment

The goal of this observational study is to learn whether noninvasive real-time arterial waveform monitoring can be used to assess cardiovascular diseases in adults. The main question it aims to answer is: Can photoacoustic imaging accurately capture arterial waveforms from patients' fingers? Can features extracted from the arterial waveforms reflect …

18 - 80 years of age All Phase N/A

Perioperative EEG-Monitoring and Postoperative Delirium in Patients Undergoing Cardiovascular Surgery

Postoperative delirium is common in patients undergoing cardiovascular surgery and associated with poor outcomes. However the pathogenesis of postoperative delirium is poorly understood. Multichannel electroencephalogram is a recognized tool for identifying neurophysiologic states during anesthesia, sleep, and arousal. The aim of the current study is to evaluate the mechanisms and …

18 years of age All Phase N/A
A Anna Maria Malagoni, Dr

Cardiovascular Prevention Supported by Digital Technology: Comparison With the Traditional Model

Cardiovascular diseases represent one of the leading causes of morbidity and mortality worldwide. Prevention in patients at cardiovascular risk is essential to reduce the incidence of cardiovascular events and slow the progression of risk. This study aims to evaluate the effectiveness and feasibility of a cardiovascular prevention pathway delivered remotely …

40 - 75 years of age All Phase N/A
A Alessandro Pini, MD

Genetic Aortic Diseases and Cardiovascular Complications. An Observational Survey of Risk Factors.

The aim of this observational study is to define the behavioural and cardiovascular risk factor profiles of patients with genetic aortopathies. The main questions it aims to answer are: How do the interconnections between lifestyle, stress, psychological condition, perception of illness, and state of health influence each other in this …

14 - 60 years of age All Phase N/A

Home-Based Heat Therapy in Spinal Cord Injury to Improve Cardiovascular Health

The study is designed to investigate the effects of passive heat therapy on blood vessel health in 40 people (48 enrolled with attrition rate of 20%). Following an extensive set of vascular function tests, participants will engage in either a passive heat therapy intervention for 60 minutes, 4 times a …

18 - 60 years of age All Phase N/A

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