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Found 64,783 clinical trials
J Jeffrey Cheng, MD, PhD

Immune Spatial Features of Guselkumab Cutaneous Response

This study examines the effect of IL-23 blockade with Guselkumab on the immune cells of scalp psoriasis lesions.

18 years of age All Phase 4

Improving Bowel Function and Quality of Life After Spinal Cord Injury

Bowel dysfunction is consistently rated as one of the most common complications affecting daily life for individuals with spinal cord injury. The overall objective of this study is to investigate whether the use of specific spinal cord epidural stimulation will affect bowel function. This study will also examine how alterations …

18 - 75 years of age All Phase N/A
I Ina Bergheim, Prof. Dr.

Different Dietary Patterns

The aim of the present study is to determine the effects of different standardized dietary patterns on general health markers, intestinal function, immune response and affective processes/ cognitive skills in healthy subjects.

18 - 40 years of age All Phase N/A
M Mathieu LEGENDRE

Evaluation of the Degradation of Renal Function Post Nephrectomy According to Retinal Vascularisation Parameters

Chronic kidney failure in the single remaining kidney is one of the dreaded complications of nephrectomy in patients operated on for cancer-related reasons (1). Indeed, chronic kidney disease (CKD) is associated with major cardiovascular morbidity and mortality (2). To date, there are few non-invasive methods available to predict the onset …

18 years of age All Phase N/A

Left Ventricular Unloading to Improve Outcome in Cardiogenic Shock Patients on VA-ECMO

Prospective, multi-center, randomized (1:1), controlled trial of Impella for active left ventricular unloading on top of veno-arterial extracorporeal membrane oxygenation vs. veno-arterial extracorporeal membrane oxygenation alone for the treatment of cardiogenic shock.

18 - 80 years of age All Phase N/A
L Lise Laclautre

Diffusion Tensor Brain MRI in the Detection of Structural Abnormality of the White Substance in Concussion

Concussions in sports are a major public health problem because of their frequency, and are often underdiagnosed because of an unspecific clinical picture or sometimes masked by the concussion itself. Support data has been constantly evolving in recent years, including the last publication of the Berlin Consensus in 2016 specifying …

18 years of age All Phase N/A
T Tamika Wong, MPH

Transcranial Ultrasound Via Sonolucent Cranioplasty

Transcranial Ultrasound via Sonolucent Cranioplasty is a prospective, single arm, observational, open label (non-blinded) study to collect real world evidence on the use of transcranial ultrasound via sonolucent cranioplasty.

18 years of age All Phase N/A
H Howard S. Hochster, MD

Microbiotic Product to Promote Microbiome Health and Improve Chemotherapy Delivery

This phase II trial tests whether NBT-NM108 works in reducing chemotherapy-induced diarrhea in patients with colon cancer that has spread to other places in the body (metastatic). Irinotecan is one of the most used medicine for colon cancer, but it leads to diarrhea in most patients receiving it and among …

18 years of age All Phase 2

Lactobacillus Vaginalis Capsules for Treatment of Vulvovaginal Atrophy in Young Breast Cancer Patients

This study is a prospective, randomized controlled, phase II clinical study with a planned enrolment of 60 patients. The study focuses on the efficacy and safety of Lactobacillus vaginalis capsules for the prevention and/or treatment of vulvovaginal symptoms in young breast cancer patients receiving ovarian protection during chemotherapy, in order …

18 - 45 years of age Female Phase 2

IUB SEAD RED (Revolutionary Endometrial Ablation Device Study

One of the AUB symptoms, heavy menstrual bleeding (HMB), can lead to iron deficiency and iron deficiency anemia and in acute and severe cases, can necessitate emergency medical care. This study's focus is on the symptom of HMB which has a number of benign causes. The investigative device, the IUB …

40 - 50 years of age Female Phase N/A

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