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Gemcitabine and Leflunomide in Patients With Advanced Unresectable Pancreatic Cancer

This phase Ib trial tests the safety, side effects, and best dose of leflunomide in combination with gemcitabine in treating patients with pancreatic cancer that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced) and cannot be removed by …

18 years of age All Phase 1
W Weibing Miao, MD

68Ga-JH04 PET/CT in Patients With Various Types of Cancer

As a novel radiotracer targeting fibroblast activation protein (FAP), 68Ga-JH04 is promising as an excellent imaging agent for various cancers. In this study, we observed the diagnostic performance of 68Ga-JH04 PET/CT in patients with different types of cancer, and compared its imaging results with those of 68Ga-FAPI or 18F-FDG PET/CT.

18 - 80 years of age All Phase N/A
I Iqra Khan, M.phil

Effects of Kinesiotherapy Exercises With Cervical Mobilization in Cervicobrachial Neuralgia

To evaluate the effects of kinesiotherapy exercises with cervical mobilization in Cervicobrachial Neuralgia.

30 - 50 years of age All Phase N/A

Evaluate the Efficacy and Safety of Interferon-α Combined With ATO in the Treatment of Arsenic-resistant APL

This study was a single-arm, open study. After the screening period, arsenic-resistant APL patients were treated with interferon α-2b, arsenic and venetoclax. The efficacy (ORR) and safety were evaluated.

18 - 70 years of age All Phase N/A
L Lars Vereecke, PhD

Collection of Microbiome Samples of Healthy Western Donors for Fundamental and Functional Microbiome Research

Large numbers of micro-organisms (especially bacteria) live in and on human bodies and have a very important function for the health. These microorganisms are called 'the microbiota'. They aid in the digestion of food, ensure the production of certain vitamins, and are very important for the development and regulation of …

2 - 70 years of age All Phase N/A
J Jason R. Lytle, PhD

Effect of Sex on Orthostatic Intolerance and Cardiovascular Response During Lunar Descent and Ascent

The purpose of Lunar OI (Orthostatic Intolerance) is to determine if there are differences between males and females in tolerance to and cardiovascular responses during different angles of head-up tilt simulating gravity levels less than or equal to Earth's gravity. Also, this study will determine if a gradient compression garment …

25 - 55 years of age All Phase N/A
P PEMH

Incidence of Regurgitation in Patients Undergoing Intubation in Semi-fowler v/s Supine Position

One of the most dreaded complication of general anaesthesia is aspiration of gastric contents after induction of general anaesthesia.Many endeavours and measures have been practiced to reduce the incidence of aspiration pneumonia.One such method is to intubate the patient in semi-fowler or supine posture.My study is aimed to find out …

18 - 60 years of age All Phase N/A
C Chahak Seth-Johansen, DDS

Patient Perception and Oral Function of Implant Restorations

The overall aim is to evaluate the patient-reported outcome and efficiency of replacing posterior teeth with implant-supported crowns compared to RDPs and no treatment. Sub-aims are to evaluate a new 3D-methods for registration of occlusion and to test two crown designs. Thus, the study design has three aims: To analyze …

30 years of age All Phase N/A
B Bernhard Schwabeger, MD, PhD

Neonatologist-performed Lung Ultrasound (NPLUS) to Guide Respiratory Therapy to Prevent Extubation Failure

The objective of the study is to evaluate the role of neonatologist-performed lung ultrasound (NPLUS) after weaning from invasive mechanical ventilation and extubation. Our aim is to study the diagnostic accuracy of NPLUS and investigate whether LUS leads to earlier actions before clinical deterioration and hence prevents extubation failure.

- 6 years of age All Phase N/A
G Girardin Jean-Louis, PhD

Personalized Obstructive Sleep Apnea Treatment and Effects on Alzheimer's Disease Biomarkers and Cognition Among Blacks

The purpose of this research is to see how effective the Personalized obstructive sleep apnea (OSA) Treatment Adherence Model called PRAISE is in helping the patient stick to the physician recommended OSA treatment plan Positive Airway Pressure (PAP).

60 - 85 years of age All Phase N/A

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