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Found 64,783 clinical trials
K Karim Mohamed-Noriega, M.D.

Autologous Platelet-rich Plasma (APRP) in the Treatment of Neurotrophic Keratopathy

Neurotrophic keratopathy (NK) is a condition where the cornea loses its capacity to feel pain and touch. This causes a decrease in the production of certain substances that maintain the integrity of the corneal epithelium (the most superficial layer that covers the cornea). As a result, the cornea cannot heal …

18 years of age All Phase N/A
M Marina Tolou-Shams, PhD

Family Mental Health Family Navigator Project (FMHN)

This study will focus on developing and testing a family-based mental health navigator intervention, the Family Mental Health Navigator (FMHN), to evaluate whether the intervention combined with mHealth is preliminary efficacious in improving mental health service initiation and engagement for publicly-insured youth.

6 - 17 years of age All Phase N/A
D Delphine Oudiette, PhD

Toward a Real-time Access to Sleepers' Mental Content

Sleep is crucial for global cognitive functioning, but its exact functions and mechanisms are still poorly understood. Cognitive studies of sleep typically rely on linking electrophysiological changes measured during sleep with behavioral and neural changes collected in tasks performed during wakefulness. What concomitantly happens in the mind of sleeping subjects …

18 - 35 years of age All Phase N/A
L Lukas Iselin, Dr.

Botulinum Toxin A Versus Steroids for the Treatment of Chronic Plantar Fasciitis

Plantar fasciitis is the classic and most common type of heel pain. Considering the costs for health care and the temporary disability not only for work, plantar fasciitis results in a substantial (and at least partially unnecessary) burden for the Swiss health care system and national economics. Nonoperative treatment is …

18 - 60 years of age All Phase N/A

A Study of JNJ-87189401 Plus JNJ-78278343 for Advanced Prostate Cancer

The purpose of the study is to determine the recommended regimen for Phase 2 (RP2Rs) of combination of JNJ-87189401 with JNJ-78278343 (Part 1: dose escalation) and further evaluate the safety at RP2Rs (Part 2: dose expansion) in participants with advanced prostate cancer.

18 years of age Male Phase 1
S Si Shi, PhD

APG-1387 Plus Chemotherapy in Advanced Pancreatic Adenocarcinoma

This study is a two stage study consisting of a dose escalation phase Ib and a phase II study which include subjects with previously-treated, advanced pancreatic adenocarcinoma. Dose Limiting Toxicities (DLTs) and maximum tolerated dose (MTD) of APG1387 in combination with nab-paclitaxel and gemcitabine will be evaluated in the dose …

18 years of age All Phase 1/2
N Nülüfer Erbil

The Effect of Back Massage Applied to Mothers in the Early Postpartum Period on Parameters

In the literature, there are separate studies on massage, comfort, anxiety, and physiological parameters for massage practice, but there are no studies that measure the physiological parameters of comfort, pain, anxiety, blood pressure, pulse, fever, oxygen saturation, respiratory rate in the early postpartum period. In this study, the effect of …

18 years of age Female Phase N/A
C Courtney Goodman-Capps

Effect of Flavored on!® Nicotine Pouch Products on Smoking Behaviors: a SMART

The goal of this clinical trial is to learn about the role of flavored on!® nicotine pouch products (the research products), an oral tobacco-leaf-free product, in the replacement of cigarettes with the use of the research products among adults who smoke cigarettes. The main question it aims to answer is …

22 - 65 years of age All Phase N/A

Ultrasound-guided Thyroid Cartilage Plane Block for Awake Intubation

The goal of this clinical trial is to investigate the clinical effectiveness and safety of superior laryngeal nerve block through surface injection of local anesthetic solution on the thyroid cartilage in patients undergoing general anesthesia with endotracheal intubation. The main questions it aims to answer are the effectiveness of ultrasound-guided …

18 - 65 years of age All Phase N/A
E Elin Hadler-Olsen

Management of Peri-implantitis: Non-surgical Treatment of Peri-implantitis.

The goal of this clinical trial is to compare non-surgical treatment by mechanical debridement with air-polishing in peri-implantitis. The main question it aims to answer is: • Does non-surgical treatment of peri-implantitis with an air-polishing devise (Perioflow® EMS, Nyon Switzerlad) provide a better treatment result than conventional cleaning with mechanical …

18 - 85 years of age All Phase N/A

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