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Found 64,783 clinical trials
J Jacob Karr

Unobtrusive Sensing of Medication Intake ("USE-MI")

The purpose of this study is to test the USE-MI system hardware and software to see if it can accurately measure when subjects take their HIV-related medications and help them remember to take these medications. With the use of a smartwatch and smartphone "app", investigators hope to be able to …

18 years of age All Phase N/A

Biomarkers Impact Evaluation on the Post-transplant Immune Response After Allografting of Hematopoietic Stem Cells

Chemotherapy or targeted therapy are usually used to treat hematological pathologies. Despite of medical improvement, some of these pathologies present drug resistances, or high risk of relapse. Hematopoietic stem cell (HSC) transplantation remain the gold standard of consolidation, to maintain a durable response. In this situation, allograft with hematopoietic stem …

18 years of age All Phase N/A

The NODE-202 Study (Study of Etripamil Nasal Spray in Pediatric Patients)

NODE-202 is a Phase 2, multicenter, multinational, single dose, open-label, 2-part, sequential design study in pediatric patients with an established diagnosis of paroxysmal supraventricular tachycardia (PSVT) presenting with a symptomatic episode of PSVT. In Part 1, at least 30 patients aged 12 to <18 years will be enrolled and treated …

6 - 18 years of age All Phase 2
C Christine Henri, MD

Patient SELF-management With HemodynamIc Monitoring: Virtual Heart Failure Clinic and Outcomes

To demonstrate that a virtual Heart Failure Clinic (HFC) based on patient self-management using Pulmonary Artery Pressure (PAP) monitoring is superior to usual care of HFC, leads to decreased: hospital admissions for heart failure (HF), emergency department consultation and/or unplanned intravenous heart failure therapy and cardiovascular death, compared to a …

18 years of age All Phase N/A
N Nicolas GIRERD, MD,PhD

Chronic Heart Failure - COngestion eValuation

Heart failure (HF) is a significant cause of death and the leading cause of hospitalization in patients over 65 years of age. Congestion is the main source of symptoms and the leading cause of hospitalization for HF. Furthermore, congestive signs identified in asymptomatic patients are associated with the risk of …

18 years of age All Phase N/A
L L Voorwerk, MD

Blood Sampling of Healthy Volunteers for Immunological Research

This protocol will be used to collect crucial components of the immune system from healthy volunteers for the characterization of immune cells in fresh blood. A pipeline has been set up for comprehensive immune phenotyping of both lymphoid and myeloid cells within 24 hours after blood withdrawal.

36 years of age All Phase N/A
L Lael Yonker, MD

AT1001 for the Treatment of Long COVID

The primary objective of this study is to evaluate the safety and efficacy of Larazotide (AT1001) versus placebo in children and young adults 7 to ≤21 years of age who present with symptoms of Long COVID in the presence of SARS-CoV-2 antigenemia. AT1001 (n=32) or placebo (n=16) will be administered …

7 - 21 years of age All Phase 2

Laser Acupuncture on Irritable Bowel Syndrome in Females

The aim of the study to investigate effect of laser acupuncture on constipation predominant irritable bowel syndrome in female patients

35 - 40 years of age Female Phase N/A
A Andy Yong, MBBS

A Study of Low-dose Intracoronary Thrombolytic Therapy in STEMI (Heart Attack) Patients.

Heart attacks are caused by a blood clot blocking the blood vessels of the heart, preventing blood getting to the heart muscle. Opening up the artery with a balloon (angioplasty) and a small mesh tube (stent) although life saving can cause this clot to break up and get washed downstream, …

18 years of age All Phase 3
S Sajiny John

MCG Discovery Study in Emergency Departments

This prospective discovery study is designed to demonstrate the feasibility of using an unshielded, mobile MCG device in an Emergency Department (ED) setting. The main question it aims to answer is whether interpretable data can be reliably collected as part of an ED workflow.

18 years of age All Phase N/A

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