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Found 64,783 clinical trials

A Study on the Anti-Wrinkle Efficacy Assessment and Safety Evaluation of the Cluster of Autologous Dermal Fibroblast on Bilateral Crow's Feet

This study is a phase 1/2 clinical trial to evaluate the safety and efficacy of administering clusters of autologous dermal fibroblasts to subjects with periorbital wrinkles on both sides. If subjects who have signed the Informed consent form voluntarily are enrolled in this study, they will be tested for eligibility …

19 years of age All Phase 1/2

Immunotherapy and Irreversible Electroporation in the Treatment of Advanced Pancreatic Adenocarcinoma

Compare the efficacy and tolerability of irreversible electroporation in combination with Nivolumab in patients with locally advanced pancreatic cancer.

18 years of age All Phase 2
A Aarika Sheehan, PT, DPT

Feasibility of Sensory Feedback for Lower Limb Amputees

The purpose of this study is to evaluate the effectiveness of providing sensation of the missing limb to individuals with lower limb loss, including above and below knee amputees. The approach involves delivering small electrical currents directly to remaining nerves via implanted stimulating electrodes. These small electrical currents cause the …

18 years of age All Phase N/A
T Tatia Mei-chun LEE, PhD

The Effects of Transcranial Direct Current Stimulation (tDCS) in Older Lonely Individuals

This randomized clinical trial aims to test the effects of 10 sessions of transcranial direct current stimulation (tDCS) on social and emotional functions in lonely older adults. The main objectives include: Understand whether tDCS could successfully boost positive social processing and social motivation in older adults, paralleling its effect on …

60 years of age All Phase N/A
J Jeremy Spencer, BSc, PhD

Impact of Pomegranate Seed Oil on Postprandial Cardiovascular Disease Risk Markers

Dietary fat plays a crucial role as a modifiable risk factor influencing both non-fasting lipaemia and vascular reactivity. Notably, the intake of dietary saturated fatty acids (SFAs) has been associated with adverse effects on blood lipid profiles, whereas increased consumption of unsaturated fatty acids (UFAs) has shown potential to improve …

- 65 years of age Female Phase N/A
H Huikai Li, MD

Cadonilimab Plus Regorafenib and Gem-Cis Chemotherapy in Advanced Biliary Tract Cancer

To evaluate the efficacy and safety of Cadonilimab in combination with Regorafenib and Gem-Cis chemotherapy in advanced biliary tract Cancer

18 - 75 years of age All Phase 2
P Pui Wah Jacqueline Chung, MBBS

Ovarian Tissue Cryopreservation and Subsequent Auto-Transplantation for Female Cancer Patients

Ovarian Tissue Cryopreservation will be provided to cancer patients to allow them to have their fertility preserved.

1 - 35 years of age Female Phase N/A

A Trial to Evaluate the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Seborrheic Keratosis

The objective of the trial is to evaluate the safety and efficacy of SM-020 gel 1.0% in subjects with Seborrheic Keratosis (SK) compared to vehicle gel. It is a randomized, double-blind, vehicle-controlled trial. Approximately 60 subjects will be enrolled. Subjects will apply their assigned investigational product twice daily for 4 …

18 years of age All Phase 2
W Wietse Claeys, MD, PhD

Patient Reported Outcome on Genital Sensitivity and Sexual Function After Genital Gender Affirming Surgery

For genital gender affirming surgery, it remains unclear to what extent genital sensitivity might be expected and what the impact of this might be on sexual functioning.

18 - 110 years of age All Phase N/A
P Pertti M Pirttiniemi, Professor

Early Crossbite Correction - a Randomized Study

The aim of this longitudinal randomized investigation is to determine the long-term effects of early lateral crossbite correction with Quad-Helix appliance, during the deciduous dentition, on craniofacial structures and dental arches, compared to treatment started later, after the first permanent molars have erupted. The hypothesis is that the timing of …

5 - 18 years of age All Phase N/A

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