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Found 65,447 clinical trials

Open Versus Laparoscopic Repair of Perforated Peptic Ulcer

The aim of this clinical trial is to compare the outcomes of open versus laparoscopic repair for perforated peptic ulcer and provide evidence-based guidance to the selection of the most appropriate operative technique at Sohag University Hospital. The study will include patients presented with perforated peptic ulcers as a complication …

years of age All Phase N/A
N Nancy Kuntz, MD

A Study to Assess the Efficacy and Safety of Empasiprubart Versus IVIg in Adults With Multifocal Motor Neuropathy

The main purpose of this study is to compare empasiprubart and IVIg in adult patients with MMN. The study consists of a double-blinded part A (empasiprubart, IVIg) and an open-label part B (empasiprubart). The maximum study duration for participants is up to 49 months.

18 years of age All Phase 3
L Lindsay Diamond

A Trial of Durvalumab (MEDI4736) Plus Monalizumab in Non-Muscle-Invasive Bladder Cancer

This is a phase 2 open-label two cohort study of durvalumab plus monalizumab in patients with BCG-unresponsive or BCG-exposed CIS NMIBC. Arm A will enroll 43 participants who have cancer in situ (CIS) with or without high grade papillary urothelial cancer. Arm B will enroll 17 participants who do not …

18 years of age All Phase 2

Effects of Intermittent Running on Metabolic Health

The purpose of this study is to investigate the suitability of intermittent exercise of long and short intervals at lower intensities than HIIE on energy expenditure during and post-exercise compared to MICE, as well as determine whether similar or greater effects can be achieved for glycemic control in recreationally active …

20 - 45 years of age Male Phase N/A
C Cassandra Heslin

LH-001 vs Placebo in Healthy Participants

The purpose of this clinical trial is to evaluate the safety and tolerability of LH-001 when administered as an oral, single or multiple dose(s) at ascending dose levels in healthy participants.

18 - 60 years of age All Phase 1
S Sabine Krumm

Acute Oral Ketone Monoester Supplementation and Resting-state Brain Connectivity

The primary objectives of this pilot study are to test if a single dose of an oral ketone monoester supplement will increase blood flow and connectivity in the brain in adults with subjective cognitive decline (SCD) or mild cognitive impairment (MCI). The main questions it aims to answer are: Does …

55 years of age All Phase N/A
M Meltem Çapar, Specialst

The Effect of Reminiscence Therapy in Elderly

In this study titled "Psychological Well-Being and Awareness in the Elderly: The Effect of Reminiscence Therapy", patients will be randomly divided into two groups as experimental and control groups. No intervention will be made to the patients in the control group. Reminiscence therapy will be applied to the patients in …

65 - 100 years of age All Phase N/A
E Elena Beretta, MD

Multicenter Study That Offers New Solutions for Paediatric Rehabilitation by Proposing a Rehabilitation Plan Based on Each Child's Needs Using New Technological and Robotic Devices, Combined Among Them.

The goal of this clinical trial is to demonstrate the efficacy of multi domain robotic and technological rehabilitation on everyday life and satisfaction in children with neuromotor conditions. The main questions it aims to answer are: Will we have significant changes using the COPM in children taking part in the …

5 - 21 years of age All Phase N/A
A Anita Farha

A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers.

The purpose of this trial is to assess the safety, tolerability and between-group effect size of STIMULAN VG (with debridement) and a course of systemic antibiotics to standard of care (debridement and systemic antibiotics only) for the treatment of osteomyelitis associated stage IV pressure ulcers.

18 years of age All Phase 2
M Meltem Çapar, Specialst

Psycho-Social Effects of Gardening Activities in the Elderly

In this study titled "Psycho-Social Effects of Gardening Activities in the Elderly: A Study on Self-Esteem and Life Satisfaction", the elderly will be divided into two groups as experimental and control groups. Participants will be randomly assigned to the groups. No intervention will be made to the patients in the …

65 - 100 years of age All Phase N/A

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