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Found 295 clinical trials
M Markus Schülke-Gerstenfeld, Prof.Dr.med.

Register for Patients With Thyroid Hormone Resistance.

Thyroid hormones (TH) play a pivotal role in the development and function of the mammalian brain. Patients with impaired thyroid hormone transport into the brain tissue or in the case of defective local thyroid hormone receptor (collectively referred to as thyroid hormone resistance) subsequently experience psychomotor disabilities. The "DEEPTYPE" registry …

years of age All Phase N/A

Ultrasound-guided Thermal Ablation for Recurrent Thyroid Cancer

To evaluate the long-term outcomes of ultrasound-guided thermal ablation for recurrent thyroid cancer

18 years of age All Phase N/A
J Joanna Rymuza, MD, PHD

Tocilizumab in Corticosteroid-Resistant Graves' Orbitopathy (Thyroid Eye Disease)

The aim of this study is to evaluate the efficacy and safety of Tocilizumab as second/third line treatment in patients with Active Moderate-to-Severe Corticosteroid-Resistant Thyroid Eye Disease.

18 - 80 years of age All Phase N/A
E Emad Z Kamel, M.D.

Throid Dysfunction in Liver Failure and Its Eddects Upon Outcome

Liver plays an important role in the metabolism of thyroid hormones, as it is the most important organ in the peripheral conversion of tetraiodothyronine (T4) to triiodothyronine (T3) by Type 1 deiodinase.

18 - 60 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Clinical and Genetic Studies in Familial Non-medullary Thyroid Cancer

Background Researchers are studying types of thyroid cancer that seem to cluster in families. Non-medullary thyroid cancer accounts for the vast majority of all types of thyroid cancer, but little is known about possible genes that may cause the cancer. More research is needed to develop the best ways to …

7 - 90 years of age All Phase N/A

Natural History Study of Children and Adults With Medullary Thyroid Cancer

Background Medullary thyroid cancer (MTC) is a rare cancer of the thyroid gland. In children and adults, it is often part of a condition called Multiple Endocrine Neoplasia 2 (MEN2). MEN2 is usually caused by a genetic mutation, and it can cause a number of problems in addition to MTC. …

4 years of age All Phase N/A

Different Models of Tracheal Catheters Are Used for Female Thyroid Glands

Objective:Compare whether the use of tracheal catheters of models 6.0 and 6.5 causes less sore throat in women after thyroid surgery compared with the traditional use of model 7.0 tracheal catheters.Methods:Investigators enrolled 180 female patients with American Society of Anesthesiologists (ASA) physical status I and III, aged 18-65 years, and …

18 - 65 years of age Female Phase N/A

Interest of the SPECT-CT Scan SUVspect in the New Generation of Gamma-cameras With Semiconductor

Since 2017, a revolution began in the departments of nuclear medicine, with the routine use of gamma-cameras with semiconductor. These gamma-cameras (which obtained the CE-marking in 2016), offer a technological breakthrough by providing an additional information. They allow "to quantify" for the 1st time in clinical routine conditions, the quantity …

18 years of age All Phase N/A
J Jennifer H Kuo, MD MS

RFA of Benign Thyroid Nodules: Clinical Outcomes and Quality of Life Study

The purpose of this observational research is to evaluate and compare clinical outcomes after treatment for symptomatic benign multinodular goiter (MNG) patients. This is a data collection study in which we ask participants to give access to information generated before and after treatment of their condition.

18 years of age All Phase N/A
S Shimaa A Meshaal, MD

Thyroid Dysfunction and Its Association With Metabolic Dysfunction-Associated Fatty Liver Disease

This study aims to evaluate the prevalence of thyroid dysfunction and its association with metabolic dysfunction-associated fatty liver disease.

18 years of age All Phase N/A

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