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Found 64,783 clinical trials
W Weiguo Lv, Doctor

Fuzuloparib Arsenic Trioxide Platinum Resistance Relapsed Ovarian Cancer

Ovarian cancer is the leading cause of death from gynecologic tumors in the western world. Most patients have relapses, and responses to subsequent therapies are generally short-lived. Currently, the population that can benefit from PARPi is mainly focusing on BRCAm, then homologous-recombination deficiency patients. Limited data revealed the ORR was …

18 - 70 years of age Female Phase 1/2
S Sheng-Li Xue, M.D.

Study of Venetoclax Combined With Azacitidine Regimen in Newly Diagnosed T-ALL Patients

The purpose of this study is to evaluate the efficacy and safety of venetoclax combined with azacitidine regimen for newly diagnosed T-ALL patients.

15 years of age All Phase 2
H Harry Marshall, MD/PhD

Gadoxetate Abbreviated MRI in Metastatic Colorectal Cancer

After a patient is diagnosed with colon cancer, they receive a CT of the chest, abdomen, and pelvis to see if the cancer has spread (metastasized) to other parts of the body. A common site for the cancer to spread to is the liver. If an abnormality is seen in …

18 years of age All Phase N/A
C Clinical Trial Coordinator

A Trial Evaluating Patient Preference of Dropless vs Drops Post Cataract Surgery

To evaluate the safety and ocular efficacy of Dextenza in combination with an intracameral antibiotic and NSAID in controlling post-operative ocular pain and inflammation compared to standard of care topical therapy in patients undergoing bilateral cataract surgery.

22 - 100 years of age All Phase 4
R Rose Arrieta

Comparison of Surgery and Medicine on the Impact of Diverticulitis (COSMID) Trial

The COSMID (Comparison of Surgery and Medicine on the Impact of Diverticulitis) trial is a pragmatic, patient-level randomized superiority trial of elective colectomy vs. best medical management for patients with quality of life (QoL) limiting diverticular disease. A parallel observational cohort will include those who are disinclined to have their …

18 years of age All Phase N/A

Large Artery Occlusion Treated in Extended Time With Mechanical Thrombectomy Trial

A multi-center, prospective, randomized, open-label, adaptive group sequential designed, blinded endpoint assessment (PROBE) clinical trial of endovascular treatment among selected AIS

18 years of age All Phase N/A
P Patrick PLADYS, Pr

Apnea Treatment in Premature Infants Using an Automatic Vibro-tactile Stimulator Triggered by the Detection of Apnea-bradycardia.

The goal of the SENSITACT system is to activate an adaptive kinesthetic stimulation to treat apnea-bradycardia events on preterm infants, while minimizing deleterious effects, in particular arousals that can be due either to respiratory efforts or to kinesthetic stimulation itself. This novel system will provide an alternative treatment to apnea-bradycardia, …

34 - 36 years of age All Phase N/A
J Jyrki AO Kössi, Adjunct Prof

Day Case Colectomy: Optimizing Short Stay-surgery.

HRV measurement of patients recovering from laparoscopic colorectal resection for any pathology.

18 - 100 years of age All Phase N/A
C Carolin Steinack, MD

Noninvasive Early Detection of Lung Allograft Dysfunction After Lung Transplantation With Multiple Breath Washout Test

Chronic rejection, more commonly called bronchiolitis obliterans syndrome (BOS), is the leading cause of death beyond the first year post lung transplantation. The diagnosis of BOS is typically made by clinical, physiological, and radiographic parameters. Early detection would be desirable since it allows treatment modification to stop or delay the …

18 years of age All Phase N/A

Integrated Treatment in FND (Functional Neurological Disorders)

The project will investigate the effectiveness of patient-centered integrated treatment. The correlations between physiotherapy indices, non-invasive brain stimulation, connectivity and psychological support will be analyzed.

18 - 65 years of age All Phase N/A

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