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Found 65,447 clinical trials

Post-marketing Re-evaluation of WangBi Granules for Rheumatoid Arthritis

The group used a randomized controlled trial to conduct a post-marketing re-evaluation study of Wangbi granules. The study was conducted to observe the degree of clinical remission in rheumatoid arthritis patients with low disease activity after standard methotrexate and tofacitinib citrate treatment, using a combination of Chinese and Western medicine …

18 - 75 years of age All Phase 4

Efficacy of Microparticle Geniculate Artery Embolization in Total Knee Prosthesis Patients With Pain Resistant to Medical Treatment. A Prospective Randomized Controlled Trial

The goal of this clinical investigation is to evaluate the effectiveness on pain of arterial occlusion (embolization) of neovessels by microparticle in a double-blind sham controlled randomised trial in patients with persistent pain on a total knee prosthesis (TKP), inserted for gonarthrosis, despite well-conducted medical treatment. The study patient population …

40 - 80 years of age All Phase N/A
M Matthijs Moerland, PhD

A First-in-human Study of the Safety of an Immunosuppressive Antibody (IMP761) in Healthy Volunteers

The goal of this clinical trial is to evaluate the safety and tolerability of single and multiple doses of IMP761 in healthy female and male volunteers aged 18-55 with no history of disease affecting the immune system or recent use of medication with effects on the immune system. The main …

18 - 55 years of age All Phase 1
S Simone Bruno

Neuromodulation-assisted Ego-disengagement: The NEURO-EGO Study Stage 1

The goal of this clinical trial is to learn whether brain stimulation technology can help people reach a meditative state quickly and easily without years of meditation training. The researchers want to see if this will help people distance themselves from their thoughts and feeling, and if this will lead …

18 - 80 years of age All Phase N/A
M Markeela Lipscomb, CCRC

Efficacy & Safety of LOBO™ Vascular Occlusion Device for Embolization of Pulmonary Arteriovenous Malformations

The goal of this clinical trial is to evaluate both the technical success and efficacy of using the LOBO™ device in patients undergoing embolization of Pulmonary Arteriovenous Malformations (PAVM). The main question[s] it aims to answer [is/are]: What is the technical success rate, the number of LOBO™ devices needed for …

14 years of age All Phase N/A
M Mengyang Di, MD, PhD

Odronextamab for Relapsed and Refractory Large B-cell Lymphomas Before CAR-T

This phase II trial tests the effectiveness of odronextamab given before chimeric antigen receptor T (CAR-T) cell therapy (bridging therapy) in patients with large B-cell lymphomas that have come back after a period of improvement (relapsed) or that have not responded to previous treatment (refractory). Odronextamab is a bispecific antibody …

18 years of age All Phase 2
A ADIYAMAN EDUCATION AND RESEARCH HOSPITAL

Three Dimensional Virtual Reconstruction (3D) in Percutaneous Nephrolithotomy

The aim of our study is to investigate the effect of 3D imaging technique on the PCNL learning curve in specialist training.

18 years of age All Phase N/A

Optimal Bowel Preparation in Geriatric Patients With a Instructional Animation Video Before Colonoscopy

Our study presents an innovative educational approach combining visual and auditory elements, targeting the specific needs of the geriatric population. Generally, before colonoscopy, participants are given a written instruction describing the standard bowel preparation with the use of laxatives and enemas. In our study, in addition to this written instruction, …

60 years of age All Phase N/A

Taste Alterations Study

The main questions it aims to answer are: Does completing a standard assessment increase the detection of chemotherapy induced taste changes compared with usual care (no assessment)? What TA are experienced? Are there any patterns in TA symptom occurrence based on age, sex, race/ethnicity, cancer type, chemotherapy agent, etc. Do …

18 years of age All Phase N/A
A Ashley Scherer

A PIVOTAL STUDY EVALUATING SAFETY and EFFICACY of the SHIRATRONICS MIGRAINE THERAPY SYSTEM

Prospective, multi-center, double blind, randomized, sham-controlled study to evaluate neuromodulation in patient with chronic migraine. The study hypothesis to be tested is the mean reduction in mean monthly headache days between patients in treatment versus sham.

22 years of age All Phase N/A

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