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Found 919 clinical trials
A Alexander Egbe, MBBS, MPH

A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial)

The purpose of this study is to evaluate the effectiveness and mechanism of action of Losartan in the treatment of coarctation of aorta.

18 years of age All Phase 3
P Parham Sadeghipour, MD

Feasibility of a Multifaceted Program to Reduce Cardiovascular Complications of Air Pollution

The main goal of this clinical trial is to evaluate the feasibility of conducting a large-scale clinical trial testing a program containing several aspects for reducing the effects of air pollution on cardiovascular health (which is named the hybrid program hereafter) in adult patients (18 years or older) with atherosclerotic …

18 years of age All Phase N/A
D Dr Zuriati Ibrahim, PhD

Date Seed Extract Effectiveness in Controlling Diabetes and Cardiovascular Risk in T2DM

Globally, chronic noncommunicable diseases rank as the leading cause of morbidity and mortality. Diabetes is reaching high epidemic proportions across the globe. The prevalence of diabetes is increasing in Saudi Arabia, with diabetes affecting 14.1% of the population across all age groups and 28% of those over the age of …

18 - 80 years of age All Phase N/A
M Myles W O'Brien, PhD

Managing Frailty Through Mobilization in Males and Female Inpatients with Cardiovascular Disease

Frailty describes the overall health of a person. Inpatients with cardiovascular problems have a higher risk for frailty - or the sick are more likely to get sicker - causing longer hospital stays, hospital readmission, and death. Females are particularly vulnerable to these problems, generally displaying higher frailty levels than …

18 years of age All Phase N/A
S Stephen Ives, Ph.D.

Impact of Sex in the Effect of Dietary Capsaicin on Cardiovascular Health

The investigators long-term goal is to better understand novel interventions to promote cardiovascular health in humans. The goal of the proposed research is to investigate whether there is sex-specificity in the effects of dietary capsaicin on mechanisms regulating nitric oxide (NO) bioavailability, its effect on key markers of cardiovascular (CV) …

18 years of age All Phase N/A

Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health

The goal of this clinical trial is to evaluate whether disclosure of a non-high polygenic risk score for coronary artery disease (CAD PRS) is non-inferior to standard of care in maintaining cardiovascular health over one year among adults aged 40-75 years without cardiovascular disease and not on statins.

40 - 75 years of age All Phase N/A
L Livia B Andrade, phD student

Effectiveness of a Intraoperative Blood Recovery System in Cardiovascular Surgery in Brazil

Randomized trial to evaluate the effectiveness of a intra operative blood recovery system in reducing the need for allogeneic transfusion in cardiovascular surgeries using cardiopulmonary bypass

18 years of age All Phase N/A
V Valentina Totti, PhD

Exercise and Diet Effects in Reducing Cardiovascular Risk in Kidney Transplant Recipients

The goal of this clinical trial is to assess whether, over an observation period of 3 years, there is a reduction in cardiovascular risk, and the extent of this reduction, in a group of adult kidney transplant patients undergoing tailored exercise combined with dietary counselling compared to a group of …

30 - 69 years of age All Phase N/A

Time-restricted Eating Study (TRES): Impacts on Anthropometric, Cardiometabolic and Cardiovascular Health

The goal of this clinical trial is to learn about the effects of time-restricted eating in patients with history of acute coronary syndrome. The main questions it aims to answer are: 1) Is 10-hr TRE safe and feasible for patients with ACS; 2)What are the impacts of 10-hr TRE on …

18 - 65 years of age All Phase N/A
A Andrew Stone

Assessment and Prediction of Cardiovascular Health and Disease Risk Using Wearable Biometrics.

This prospective, observational cohort study will evaluate the associations between wearable-derived biometrics and cardiovascular health, quantified by the American Heart Association's Life's Essential 8 framework, as well as related cardiovascular risk factors. The study aims to determine whether wearable biometrics can support the assessment of cardiovascular health and cardiovascular disease …

18 years of age All Phase N/A

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