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Found 1,651 clinical trials

The Effect of Dual-task Training on Balance, Exercise Capacity, Cognitive Status, and Quality of Life

The aim of this study is to investigate the effects of dual-task training on balance, exercise capacity, cognitive function, and quality of life in individuals with Type 2 Diabetes Mellitus (DM). As a result of this study, it is hoped that dual-task training will be an alternative to single-task training …

65 years of age All Phase N/A
H Hongmei Zhang, PHD

The Effects of Henagliflozin on Glucose Fluctuation and Immunosenescence in Type 2 Diabetes Patients on Insulin Therapy

The goal of this clinical trial is to learn if SGLT2 inhibitor Henggliflozin works to improve glucose variability in type 2 diabetes and if Henggliflozin can benefit immunosenescence. The main questions it aims to answer are: Does Henggliflozin as an add on treatment works to improve blood glucose fluctuation in …

50 - 70 years of age All Phase 4

A Study to Test How Insulin NNC0471-0119 H Works in the Body in Participants With Type 2 Diabetes When Given by an Insulin Pump

This study looks at the effect and safety of a new fast-acting insulin (NNC0471-0119) in people with type 2 diabetes when given by an insulin pump. The study tests how fast insulin NNC0471-0119 enters bloodstream, how long it stays there and how much it lowers blood sugar. The new insulin …

18 - 69 years of age All Phase 1

Study of Duodenal Mucosal RF Vapor Ablation in Subjects With Type-2 Diabetes Mellitus

The purpose of this clinical study is to test the hypothesis that RF vapor ablation of the duodenal mucosa will result in improvement in glycemic parameters, without complications (bleeding/ stricture / perforation). The main aims of the study are : Evaluate the safety of the device and procedure based on …

18 - 65 years of age All Phase N/A
R Research coordinators

App-based Diabetes Management and Community-based Interventions

Community-based health coaching interventions play a vital role in complementing the traditional chronic disease management model for type 2 diabetes patients. Compared to conventional approaches that often focus on periodic clinical visits, community-based coaching could provide continuous, personalised support within patients in everyday environments. Health coaches work directly with patients …

21 years of age All Phase N/A

Multiple Dose Study of MK-2828 in Participants With Type 2 Diabetes (MK-2828-003)

The purpose of this study is to learn about the safety and if people tolerate a study medicine called MK-2828. The study will also measure what happens to MK-2828 in the body of a person with type 2 diabetes (T2D) over time (pharmacokinetic or PK study), and how it affects …

24 - 75 years of age All Phase 1
M Mathew M Thambi, PharmD, MPH

Effect of Continuing Versus Holding Metformin During Hospitalizations.

A randomized study of continuing versus holding metformin during hospitalizations to internal medicine services to determine the effects on glucose control, acidosis, abdominal symptoms, length of stay, and mortality.

18 - 110 years of age All Phase 4
D Dwirini R Gunarti

The Effect of Propolis Administration on Cholesterol Level in Diabetic Type 2 Patients

The goal of this clinical trial is to learn if propolis administration works to change the level of Low Density Lipoprotein (LDL) and High Density Lipoprotein cholesterol (HDL) in diabetic type 2 patients. The main questions it aims to answer are: Is giving 1 drops/ 10kg/ times, twice daily for …

35 - 59 years of age All Phase 4
M Matthias Hepprich, MD

Dapansutrile in Diabetes and Diabetes-Related Complications - Dapan-Dia

The aim of the study is to determine whether NLRP3 inhibition with dapansutrile represents a new pharmacological option for diabetes management with potential as an anti-inflammatory agent to also address micro- and macro-vascular risk and complications from diabetes.

18 - 75 years of age All Phase 2
S Shiyun Wang, PhD

Effects of Real-time Continuous Glucose Monitoring System on Hospital-to-home Transitional Blood Glucose Control

Glucose monitoring is an important part of self-management for patients with diabetes. The results of glucose monitoring not only help to assess the degree of glucose metabolism disorders in patients, but also help physicians to make clinical decisions and guide patients in self-management. Despite extensive efforts and advances in diabetes …

18 - 80 years of age All Phase N/A

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