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Found 64,783 clinical trials
W Winnie Samy, RN, BN, MSc

Minimum Effective Local Anesthetic Volume for Ultrasound Guided Superior Trunk Block

The objective of this study is to identify the minimum effective dosage of a commonly used local anaesthetic drug "levobupivacaine" required to produce an effective ultrasound guided (USG) superior trunk block (STB) in at least 90% of patients for shoulder arthroscopic surgeries.

18 - 75 years of age All Phase N/A

Predicting Response to Neoadjuvant ATEZOLIZUMAB Plus Carboplatin/Nab Paclitaxel in Resectable Non-squamous NSCLC

Exploratory study evaluating the potential of immune signature profiling for predicting response in patients with resectable Stage II, IIIA and select IIIB (T3N2 only) non-squamous Non-Small Cell Lung Cancer (NSCLC) to neoadjuvant ATEZOLIZUMAB plus Carboplatin/nab Paclitaxel Atezolizumab is given as intravenous infusion at a fixed dose of 1200 mg, day …

18 years of age All Phase 2

Efficacy and Safety of Rivaroxaban in the Prevention of Venous Thromboembolism in Glioma Patients

Glioma is a common brain tumor with a high risk of venous thromboembolism during treatment, especially in the months after surgery. Postoperative lower extremity dyskinesia in patients with gliomas is considered as a high-risk factor for venous thromboembolism. Rivaroxaban, as an oral anticoagulants, has similar effect in the prevention and …

18 - 80 years of age All Phase N/A
R Roberta Adorni, PhD

Efficacy of a Tailored Communication Intervention Aimed at Increasing the Number of Daily Steps

This study aims to evaluate the efficacy of a physical activity promotion intervention focused on walking behavior. The intervention is delivered via mobile application in a sample drawn from the healthy adult population.

18 - 70 years of age All Phase N/A
C Chieh-Hsin Lin, MD, PhD

DAOIB for the Treatment of Brain Fog

This is a 24-week open trial. We will enroll long-COVID patients with cognitive impairments. All patients will receive DAOIB for 24 weeks. We will assess the patients every 8 weeks during the treatment period (weeks 0, 8, 16, and 24). We hypothesize that DAOIB treatment will be beneficial in improving …

18 - 100 years of age All Phase 2
D Dorline Sokoundjou, MSc

Autologous Cultured Corneal Epithelium (CECA) for the Treatment of Limbal Stem Cell Deficiency

The study " Autologous cultured corneal epithelium (CECA) for the treatment of corneal lesions associated with limbal stem cell deficiency" is the first clinical trial of this product manufactured at the LOEX laboratory. The culture of corneal epithelium strives to produce a reconstructed tissue with the therapeutical aim of treatment …

1 years of age All Phase N/A
H Hannah Block, PhD

Neural Basis of Sensory Learning: Brain Regions

The purpose of this study is to understand how the sensory and motor areas of the brain work together to keep a person's hand movements accurate (sensorimotor learning). The investigators hope this information may be useful one day to improve rehabilitation techniques in patients with brain lesions.

18 - 45 years of age All Phase N/A
Z Zeynep Kızılcık Özkan

The Effect of Oral Cold Water Spray Application on Thirst Severity in Patients Undergoing Spinal Surgery

The aim of this study was to determine the effect of oral cold water spray application on thirst severity and patient satisfaction after spinal surgery. H1: Oral cold water spray application has an effect on thirst severity after spinal surgery. H2: Oral cold water spray application has an effect on …

18 years of age All Phase N/A

Endo-epicardial vs Endocardial-only Catheter Ablation of Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy (EPIC-VT)

Radiofrequency ablation of ventricular tachycardias (VTs) is the gold standard treatment of refractory VTs in patients with ischaemic heart disease. In this setting, ablation is usually performed endocardially. However, even after a procedural success there is a high risk of recurrence, particularly due to the inability to create transmural lesions. …

18 years of age All Phase N/A
A Allen Lee, MD, MS

A Pilot Study Examining Low Sulfur Diet as Treatment for Persistent Symptoms in Quiescent Crohn's Disease

The goal of this study is to learn about a low sulfur diet in patients with Crohn's disease. Study participants will be randomized to receive a low sulfur diet or usual diet for 8 weeks. Participants will work with study nutritionists and receive dietary educational materials. Participants will attend 2 …

18 years of age All Phase N/A

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