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Found 64,783 clinical trials
A Anissa MEGZARI

Clinical Development of a Tool for Optimized Self- and Hetero-diagnosis of Stroke Using Artificial Intelligence: Stage1- Collection of Video-clinical Data in a Pragmatic Situation.

The study authors aim to form a collection of video-clinical data in a pragmatic situation to enable the development of relevant AI algorithms (for both hetero- and self-diagnosis modes). The aim is to optimize management through early diagnosis (self- and hetero-diagnosis) and thus to reduce sequelae disability. The study authors …

18 years of age All Phase N/A
A Ana MD Sebio

Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma (SeliSarc)

Phase I-II, non-randomized, single-arm, open-label, multicenter, international clinical trial. Patients with advanced soft-tissue sarcoma (leiomyosarcoma or malignant peripheral nerve sheath tumor) will receive selinexor in combination with gemcitabine.

18 - 80 years of age All Phase 2
M Manuel Taboada

Early vs Delayed Extubation After Endovascular Treatment for Acute Ischemic Stroke

Although older studies, most of them retrospective in design, advocated sedation over general anesthesia during endovascular treatment for acute ischemic stroke, a recent meta-analysis and randomized studies have shown that general anesthesia is associated with better functional status at 3 months compared with local anesthesia and sedation. In our center, …

18 years of age All Phase N/A
G Gary M Cox, MD

Stool Transplants to Treat Refractory Clostridium Difficile Colitis

It has been shown that restoration of the normal makeup of the bowel bacterial population is the most effective way to treat recurrent colitis due to Clostridium difficile. Restoration of the normal bowel bacterial population is best done by transplanting stool from a healthy donor. The investigators wish to transplant …

18 years of age All Phase 2
S Sainan Shu, PhD

Fecal Microbiota Transplantation in Pediatric Ulcerative Colitis (UC)

This study included two topics: one was to test the efficacy and safety of fecal microbiota transplants plus partial enteral nutrition (PEN) in refractory pediatric UC where conventional therapy has failed, and the other was to explore the efficacy and safety of FMT plus PEN as first-line therapy for pediatric …

2 - 16 years of age All Phase N/A
J Jenny QIU, MD

Slow Myopia Progression With Different Irradiance Light

It is a prospective clinical control study on red light control myopia with specail design spectacles for 75 children in 3 groups. Study Groups with two different powers of 0.6 mW and 1.2 mW at wavelength of 650nm. The control group is to wear the same brand and design spectalces …

6 - 12 years of age All Phase N/A
Y Yael Sharon, MD

A Clinical Study to Evaluate the Potential Role of ACTH Gel in Patients With Scleritis

ATLAS study is a clinical trial to evaluate the potential role of subcutaneous adrenocorticotropic hormone (ACTH) gel in the management of non-infectious scleritis. Specifically, the ATLAS Study aims to evaluate the safety, tolerability and effect of 2 different dose regimens of ACTH gel administered by subcutaneous (SC) injection in patients …

18 years of age All Phase 2
J Jeannette Devoto

Olinvacimab With Pembrolizumab in Patients With mTNBC

The objective is to evaluate the efficacy and safety of Olinvacimab in combination with Pembrolizumab in patients with mTNBC.

19 years of age All Phase 2
D Dmitry Balashov, MD, PhD

Low Dose Treosulfan Based Conditioning Regimen and PTCy in HSCT for Nijmegen Breakage Syndrome

The aim of the current study is to evaluate the safety and efficacy of low dose treosulfan based conditioning regimen in HSCT with post-transplant cyclophosphamide in Nijmegen breakage syndrome

3 - 21 years of age All Phase 2
D Denise Juhr

Measurement of Bladder Pressure With a Novel External Device (Cystomanometer) - Home Use

The investigators have developed a novel pressure monitoring device that hooks to standard urinary catheters that are used by patients with a neurogenic bladder on daily clean intermittent catheterization. The device has already been demonstrated to be accurate compared to the gold standard in clinic urodynamics. This study will assess …

1 - 99 years of age All Phase N/A

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